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bcf-1 bacterial colonization factor [ Caenorhabditis elegans ]

Gene ID: 3564957, updated on 2-Nov-2024

Summary

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Official Symbol
bcf-1
Official Full Name
bacterial colonization factor
Primary source
WormBase:WBGene00019017
Locus tag
CELE_F57F4.4
See related
AllianceGenome:WB:WBGene00019017
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Located in membrane raft. Is expressed in intestine. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See bcf-1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
5
Sequence:
Chromosome: V; NC_003283.11 (6401379..6408783, complement)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Filaggrin-2-like Neighboring gene HotDog ACOT-type domain-containing protein Neighboring gene ET module Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. f57f4.4p::gfp as a fluorescent reporter for analysis of the C. elegans response to bacterial infection. Julien-Gau I, et al. Dev Comp Immunol, 2014 Feb. PMID 24012871
  2. Bacterial peptidoglycan acts as a digestive signal mediating host adaptation to diverse food resources in C. elegans. Hao F, et al. Nat Commun, 2024 Apr 16. PMID 38627398, Free PMC Article
  3. Analysis of GPI-anchored proteins involved in germline stem cell proliferation in the Caenorhabditis elegans germline stem cell niche. Rikitake M, et al. J Biochem, 2020 Dec 26. PMID 32844210
  4. Galectin LEC-6 interacts with glycoprotein F57F4.4 to cooperatively regulate the growth of Caenorhabditis elegans. Takeuchi T, et al. Biol Pharm Bull, 2011. PMID 21720028
  5. N-glycosylated intestinal protein BCF-1 shapes microbial colonization by binding bacteria via its fimbrial protein. He Y, et al. Cell Rep, 2023 Jan 31. PMID 36662624

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. f57f4.4 expression is specifically induced in the intestine upon bacterial infections, but not in response to abiotic stress.
    Title: f57f4.4p::gfp as a fluorescent reporter for analysis of the C. elegans response to bacterial infection.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
located_in membrane raft HDA PubMed 

General protein information

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Preferred Names
bacterial colonization factor
NP_504627.1
  • Confirmed by transcript evidence;
    Product from WormBase gene class bcf

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    6401379..6408783 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_072226.9 → NP_504627.1  bacterial colonization factor [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_504627.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q94247
    Conserved Domains (1) summary
    pfam01684
    Location:1401 → 1480
    ET; ET module
Nucleotide Protein
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