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D2045.9 Glycosyltransferase 25 family member [ Caenorhabditis elegans ]

Gene ID: 3565069, updated on 2-Nov-2024

Summary

Official Symbol
D2045.9
Official Full Name
Glycosyltransferase 25 family member
Primary source
WormBase:WBGene00008426
Locus tag
CELE_D2045.9
See related
AllianceGenome:WB:WBGene00008426
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable procollagen galactosyltransferase activity. Is expressed in body wall musculature; enteric muscle; and reproductive system. Human ortholog(s) of this gene implicated in brain small vessel disease 3. Orthologous to several human genes including COLGALT1 (collagen beta(1-O)galactosyltransferase 1) and COLGALT2 (collagen beta(1-O)galactosyltransferase 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See D2045.9 in Genome Data Viewer
Location:
chromosome: III
Exon count:
7
Sequence:
Chromosome: III; NC_003281.10 (10475245..10479788)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene non-specific serine/threonine protein kinase Neighboring gene Cullin-1 Neighboring gene non-specific serine/threonine protein kinase Neighboring gene BTB domain-containing protein

General protein information

Preferred Names
Glycosyltransferase 25 family member
NP_001021233.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    10475245..10479788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001026062.5NP_001021233.1  Glycosyltransferase 25 family member [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001021233.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q18989
    Conserved Domains (1) summary
    cd06532
    Location:291473
    Glyco_transf_25; Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of ...