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cox-6B Cytochrome oxidase c subunit VIb [ Caenorhabditis elegans ]

Gene ID: 3565081, updated on 2-Nov-2024

Summary

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Official Symbol
cox-6B
Official Full Name
Cytochrome oxidase c subunit VIb
Primary source
WormBase:WBGene00022170
Locus tag
CELE_Y71H2AM.5
See related
AllianceGenome:WB:WBGene00022170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 7. Orthologous to several human genes including COX6B1 (cytochrome c oxidase subunit 6B1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cox-6B in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_003281.10 (2786202..2786754)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase laf-1 Neighboring gene DNA/pantothenate metabolism flavoprotein C-terminal domain-containing protein;Myotubularin phosphatase domain-containing protein Neighboring gene Serine/threonine-protein phosphatase 2A activator Neighboring gene NADH dehydrogenase [ubiquinone] 1 subunit C2 Neighboring gene C-CAP/cofactor C-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossovers. Yokoo R, et al. Cell, 2012 Mar 30. PMID 22464324, Free PMC Article
  2. SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans. Mathies LD, et al. Proc Natl Acad Sci U S A, 2015 Mar 10. PMID 25713357, Free PMC Article
  3. Peroxiredoxin 2 is required for the redox mediated adaptation to exercise. Xia Q, et al. Redox Biol, 2023 Apr. PMID 36791646, Free PMC Article
  4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
  5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of respiratory chain complex IV IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Cytochrome oxidase c subunit VIb
NP_497618.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    2786202..2786754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_065217.8 → NP_497618.1  Cytochrome oxidase c subunit VIb [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_497618.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9BL34
Nucleotide Protein
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