U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

pigs-1 GPI transamidase component PIG-S [ Caenorhabditis elegans ]

Gene ID: 3565629, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
pigs-1
Official Full Name
GPI transamidase component PIG-S
Primary source
WormBase:WBGene00011776
Locus tag
CELE_T14G10.7
See related
AllianceGenome:WB:WBGene00011776
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be involved in attachment of GPI anchor to protein. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of GPI-anchor transamidase complex. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 95. Orthologous to human PIGS (phosphatidylinositol glycan anchor biosynthesis class S). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See pigs-1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
4
Sequence:
Chromosome: IV; NC_003282.8 (10147097..10149038, complement)

Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding protein Neighboring gene SH2 domain-containing protein Neighboring gene Tetraspanin-12 Neighboring gene ncRNA

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Increasing Complexity of the N-Glycome During Caenorhabditis Development. Wilson IBH, et al. Mol Cell Proteomics, 2023 Mar. PMID 36717059, Free PMC Article
  2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
  3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
  4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by WormBase

Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in attachment of GPI anchor to protein IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in attachment of GPI anchor to protein IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of GPI-anchor transamidase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of GPI-anchor transamidase complex IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
GPI transamidase component PIG-S
NP_001369906.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003282.8 Reference assembly

    Range
    10147097..10149038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001383182.2 → NP_001369906.1  GPI transamidase component PIG-S [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q22496
    Conserved Domains (1) summary
    pfam10510
    Location:57 → 542
    PIG-S; Phosphatidylinositol-glycan biosynthesis class S protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools