T25G3.3 60S ribosomal export protein NMD3 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: T25G3.3
Official Full Name: 60S ribosomal export protein NMD3
Primary source: WormBase:WBGene00012030
Locus tag: CELE_T25G3.3
See related: AllianceGenome:WB:WBGene00012030
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ribosomal large subunit binding activity. Predicted to be involved in ribosomal large subunit export from nucleus. Predicted to be active in cytoplasm and nucleus. Orthologous to human NMD3 (NMD3 ribosome export adaptor). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See T25G3.3 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 8

Sequence:: Chromosome: I; NC_003279.8 (7559839..7562349)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T25G3.2 (e-PCR)
- UniSTS:308118

T25G3.3 (e-PCR)
- UniSTS:311008

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ribosomal large subunit binding	IBA Inferred from Biological aspect of Ancestor more info
enables ribosomal large subunit binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in ribosomal large subunit export from nucleus	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: 60S ribosomal export protein NMD3

NP_492114.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

7559839..7562349

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059713.11 → NP_492114.2 60S ribosomal export protein NMD3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492114.2

Status: REVIEWED

UniProtKB/TrEMBL

Q22792

Conserved Domains (2) summary

COG1499
Location:15 → 391

NMD3; NMD protein affecting ribosome stability and mRNA decay [Translation, ribosomal structure and biogenesis]

pfam04981
Location:15 → 244

NMD3; NMD3 family