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Wfdc21 WAP four-disulfide core domain 21 [ Rattus norvegicus (Norway rat) ]

Gene ID: 360228, updated on 2-Nov-2024

Summary

Official Symbol
Wfdc21provided by RGD
Official Full Name
WAP four-disulfide core domain 21provided by RGD
Primary source
RGD:1303147
See related
EnsemblRapid:ENSRNOG00000029668 AllianceGenome:RGD:1303147
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Liver (RPKM 604.4), Lung (RPKM 59.8) and 3 other tissues See more
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Genomic context

See Wfdc21 in Genome Data Viewer
Location:
10q26
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (69125336..69131205)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (68627836..68633705)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (71047326..71053195)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene anosmin 1, pseudogene 1 Neighboring gene WAP four-disulfide core domain 18 Neighboring gene HEAT repeat containing 6 Neighboring gene HNF1 homeobox B Neighboring gene uncharacterized LOC134480708

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in antibacterial humoral response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
WDNM1-like protein
Names
WDNM1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001003706.3NP_001003706.2  WDNM1-like protein precursor

    See identical proteins and their annotated locations for NP_001003706.2

    Status: VALIDATED

    Source sequence(s)
    AW530516, BG661061
    UniProtKB/TrEMBL
    A1EC93, A1EC94, A6HHJ1, F7F765, Q6BEA3
    Related
    ENSRNOP00000049454.2, ENSRNOT00000042643.4

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    69125336..69131205
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)