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Tvp23a trans-golgi network vesicle protein 23 homolog A [ Rattus norvegicus (Norway rat) ]

Gene ID: 360467, updated on 2-Nov-2024

Summary

Official Symbol
Tvp23aprovided by RGD
Official Full Name
trans-golgi network vesicle protein 23 homolog Aprovided by RGD
Primary source
RGD:1566405
See related
EnsemblRapid:ENSRNOG00000079813 AllianceGenome:RGD:1566405
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fam18a; RGD1566405
Summary
Predicted to be involved in protein secretion and vesicle-mediated transport. Predicted to be active in Golgi membrane. Orthologous to human TVP23A (trans-golgi network vesicle protein 23 homolog A). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 50.5), Thymus (RPKM 21.2) and 9 other tissues See more
Orthologs
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Genomic context

See Tvp23a in Genome Data Viewer
Location:
10q11
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (5734100..5770002)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (5227198..5263185)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (5300319..5335160)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta, pseudogene 1 Neighboring gene CCHC-type zinc finger, nucleic acid binding protein, pseudogene 2 Neighboring gene uncharacterized LOC134480647 Neighboring gene NUBP iron-sulfur cluster assembly factor 1 Neighboring gene uncharacterized LOC102553451 Neighboring gene tektin 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein secretion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Golgi apparatus membrane protein TVP23 homolog A
Names
family with sequence similarity 18, member A
trans-golgi network vesicle protein 23A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108263.3NP_001101733.1  Golgi apparatus membrane protein TVP23 homolog A isoform 1

    See identical proteins and their annotated locations for NP_001101733.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6K4K0
    Conserved Domains (1) summary
    pfam05832
    Location:39180
    DUF846; Eukaryotic protein of unknown function (DUF846)
  2. NM_001393687.2NP_001380616.1  Golgi apparatus membrane protein TVP23 homolog A isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    Related
    ENSRNOP00000110455.1, ENSRNOT00000145927.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    5734100..5770002
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)