U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Luc7l LUC7-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 360503, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Symbol
Luc7lprovided by RGD
Full Name
LUC7-likeprovided by RGD
Primary source
RGD:1307542
See related
EnsemblRapid:ENSRNOG00000020488 AllianceGenome:RGD:1307542
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Luc7l1
Summary
Predicted to enable RS domain binding activity; identical protein binding activity; and mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to act upstream of or within negative regulation of striated muscle tissue development. Predicted to be part of U1 snRNP and U2-type prespliceosome. Orthologous to human LUC7L (LUC7 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 112.1), Thymus (RPKM 102.7) and 9 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Luc7l in Genome Data Viewer
Location:
10q12
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15777837..15811586)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (15273340..15307131)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15538878..15572651)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 234, member A Neighboring gene uncharacterized LOC108352066 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene small nucleolar RNA U13 Neighboring gene hemoglobin alpha, adult chain 3 Neighboring gene hemoglobin, theta 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Serine-arginine-rich nuclear protein Luc7l regulates myogenesis in mice. Kimura E, et al. Gene, 2004 Oct 27. PMID 15474286
  2. A novel SR-related protein is required for the second step of Pre-mRNA splicing. Cazalla D, et al. Mol Cell Biol, 2005 Apr. PMID 15798186, Free PMC Article
  3. Dynamic protein-protein interaction wiring of the human spliceosome. Hegele A, et al. Mol Cell, 2012 Feb 24. PMID 22365833
  4. A germline-specific class of small RNAs binds mammalian Piwi proteins. Girard A, et al. Nature, 2006 Jul 13. PMID 16751776
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RS domain binding ISO
Inferred from Sequence Orthology
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in mRNA splice site recognition IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within negative regulation of striated muscle tissue development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of U1 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2-type prespliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
putative RNA-binding protein Luc7-like 1
Names
LUC7-like 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399674.1 → NP_001386603.1  putative RNA-binding protein Luc7-like 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A6HDA0, G3V9R0, Q5FVI7
    Related
    ENSRNOP00000087424.2, ENSRNOT00000109984.2

  2. NM_001399675.1 → NP_001386604.1  putative RNA-binding protein Luc7-like 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A8I6A458, A6HDA1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15777837..15811586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086288.2 → XP_038942216.1  putative RNA-binding protein Luc7-like 1 isoform X1

    UniProtKB/TrEMBL
    A0A0G2QBZ8
    Conserved Domains (1) summary
    pfam03194
    Location:5 → 242
    LUC7; LUC7 N_terminus

  2. XM_017597369.3 → XP_017452858.1  putative RNA-binding protein Luc7-like 1 isoform X2

    UniProtKB/TrEMBL
    A0A0G2QBZ8
    Related
    ENSRNOP00000081119.1, ENSRNOT00000118201.2
    Conserved Domains (1) summary
    pfam03194
    Location:1 → 189
    LUC7; LUC7 N_terminus

  3. XM_063269322.1 → XP_063125392.1  putative RNA-binding protein Luc7-like 1 isoform X2

  4. XM_039086289.2 → XP_038942217.1  putative RNA-binding protein Luc7-like 1 isoform X2

    UniProtKB/TrEMBL
    A0A0G2QBZ8
    Conserved Domains (1) summary
    pfam03194
    Location:1 → 189
    LUC7; LUC7 N_terminus

  5. XM_039086291.2 → XP_038942219.1  putative RNA-binding protein Luc7-like 1 isoform X3

    UniProtKB/TrEMBL
    A0A0G2QBZ8
    Conserved Domains (1) summary
    cl27291
    Location:1 → 156
    LUC7; LUC7 N_terminus

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001024269.1: Suppressed sequence

    Description
    NM_001024269.1: This RefSeq was removed because currently there is insufficient support for the protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools