Rabl3 RAB, member of RAS oncogene family-like 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rabl3provided by RGD
Official Full Name: RAB, member of RAS oncogene family-like 3provided by RGD
Primary source: RGD:1306436
See related: EnsemblRapid:ENSRNOG00000026085 AllianceGenome:RGD:1306436
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable GTP binding activity; GTPase activity; and protein homodimerization activity. Predicted to be involved in several processes, including lymphocyte differentiation; protein stabilization; and regulation of Ras protein signal transduction. Predicted to be active in endomembrane system. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RABL3 (RAB, member of RAS oncogene family like 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Liver (RPKM 91.4), Kidney (RPKM 83.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 11q21

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	11	NC_086029.1 (76658723..76687681, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	11	NC_051346.1 (63153281..63182240, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	11	NC_005110.4 (66049635..66078669, complement)

Chromosome 11 - NC_086029.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

RH133956 (e-PCR)
- UniSTS:217238

RH134499 (e-PCR)
- UniSTS:217779

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	ISO Inferred from Sequence Orthology more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in B cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in T cell differentiation in thymus	ISO Inferred from Sequence Orthology more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in natural killer cell differentiation	ISO Inferred from Sequence Orthology more info
involved_in protein stabilization	ISO Inferred from Sequence Orthology more info
involved_in regulation of Ras protein signal transduction	ISO Inferred from Sequence Orthology more info
involved_in regulation of protein lipidation	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: rab-like protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.