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Polr1d RNA polymerase I and III subunit D [ Rattus norvegicus (Norway rat) ]

Gene ID: 360762, updated on 2-Nov-2024

Summary

Official Symbol
Polr1dprovided by RGD
Official Full Name
RNA polymerase I and III subunit Dprovided by RGD
Primary source
RGD:1564358
See related
AllianceGenome:RGD:1564358
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rpo1-3
Summary
Predicted to enable DNA binding activity; DNA-directed 5'-3' RNA polymerase activity; and protein dimerization activity. Predicted to be involved in DNA-templated transcription. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 2. Orthologous to human POLR1D (RNA polymerase I and III subunit D). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 231.8), Kidney (RPKM 197.6) and 9 other tissues See more
Orthologs
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Genomic context

See Polr1d in Genome Data Viewer
Location:
12p11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (13084505..13118069, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (7970592..8004157, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (9693828..9727416, complement)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095852 Neighboring gene GS homeobox 1 Neighboring gene ligand of numb-protein X 2 Neighboring gene uncharacterized LOC120095885 Neighboring gene uncharacterized LOC120095884

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC112727

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of RNA polymerase I complex ISO
Inferred from Sequence Orthology
more info
 
part_of RNA polymerase III complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
DNA-directed RNA polymerases I and III subunit RPAC2
Names
RNA polymerase 1-3
RNA polymerase I subunit D
polymerase (RNA) I polypeptide D
polymerase (RNA) I subunit D

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037787.1NP_001032876.1  DNA-directed RNA polymerases I and III subunit RPAC2

    See identical proteins and their annotated locations for NP_001032876.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098735
    UniProtKB/TrEMBL
    A0A8I6GK67, A6K1B0, F7ELN3, Q4G058

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    13084505..13118069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)