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Tmem260 transmembrane protein 260 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361030, updated on 17-Aug-2024

Summary

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Official Symbol
Tmem260provided by RGD
Official Full Name
transmembrane protein 260provided by RGD
Primary source
RGD:1562018
See related
EnsemblRapid:ENSRNOG00000013353 AllianceGenome:RGD:1562018
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562018
Summary
Predicted to be integral component of membrane. Orthologous to human TMEM260 (transmembrane protein 260). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 118.7), Adrenal (RPKM 92.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tmem260 in Genome Data Viewer
Location:
15p14
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (24213658..24287242)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (21734119..21804049)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (25294452..25361623)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102554413 Neighboring gene uncharacterized LOC120097124 Neighboring gene uncharacterized LOC102554609 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A polymorphism at the microRNA binding site in the 3'-untranslated region of C14orf101 is associated with the risk of gastric cancer development. Wang C, et al. Exp Ther Med, 2016 Sep. PMID 27602096, Free PMC Article
  2. A polymorphism at the microRNA binding site in the 3' untranslated region of C14orf101 is associated with non-Hodgkin lymphoma overall survival. Yang B, et al. Cancer Genet, 2014 Apr. PMID 24831772
  3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC188600

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables dolichyl-phosphate-mannose-protein mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein maturation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
protein O-mannosyl-transferase TMEM260
NP_001163946.2
XP_038949395.1
XP_038949398.1
XP_038949399.1
XP_038949400.1
XP_038949402.1
XP_063130465.1
XP_063130466.1
XP_063130467.1
XP_063130468.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170475.2 → NP_001163946.2  protein O-mannosyl-transferase TMEM260

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000015
    UniProtKB/TrEMBL
    A0A8I6AHR0, F1M7C0
    Related
    ENSRNOP00000017871.6, ENSRNOT00000017871.9
    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    24213658..24287242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063274395.1 → XP_063130465.1  protein O-mannosyl-transferase TMEM260 isoform X2

  2. XM_039093470.2 → XP_038949398.1  protein O-mannosyl-transferase TMEM260 isoform X4

    UniProtKB/TrEMBL
    A0A8I6AJK8, B5DEJ7
    Related
    ENSRNOP00000093081.1, ENSRNOT00000096624.2
    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

  3. XM_039093467.2 → XP_038949395.1  protein O-mannosyl-transferase TMEM260 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZTW1
    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

  4. XM_063274396.1 → XP_063130466.1  protein O-mannosyl-transferase TMEM260 isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZTW1
    Related
    ENSRNOP00000082632.1, ENSRNOT00000099556.2

  5. XM_039093472.1 → XP_038949400.1  protein O-mannosyl-transferase TMEM260 isoform X8

    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

  6. XM_063274397.1 → XP_063130467.1  protein O-mannosyl-transferase TMEM260 isoform X5

    UniProtKB/TrEMBL
    B5DEJ7

  7. XM_063274398.1 → XP_063130468.1  protein O-mannosyl-transferase TMEM260 isoform X7

  8. XM_039093471.1 → XP_038949399.1  protein O-mannosyl-transferase TMEM260 isoform X6

    UniProtKB/TrEMBL
    A0A8I5ZWL8
    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

  9. XM_039093474.1 → XP_038949402.1  protein O-mannosyl-transferase TMEM260 isoform X9

    Conserved Domains (1) summary
    pfam11028
    Location:48 → 203
    DUF2723; Protein of unknown function (DUF2723)

RNA

  1. XR_005493750.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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