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Nr2c2ap nuclear receptor 2C2-associated protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 361128, updated on 2-Nov-2024

Summary

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Official Symbol
Nr2c2approvided by RGD
Official Full Name
nuclear receptor 2C2-associated proteinprovided by RGD
Primary source
RGD:1561190
See related
EnsemblRapid:ENSRNOG00000022247 AllianceGenome:RGD:1561190
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in nucleoplasm. Orthologous to human NR2C2AP (nuclear receptor 2C2 associated protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 85.6), Kidney (RPKM 84.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Nr2c2ap in Genome Data Viewer
Location:
16p14
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (19322395..19324912, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (19288454..19290940, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (21036648..21039481, complement)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene myocyte enhancer factor 2B Neighboring gene BLOC-1 related complex subunit 8 Neighboring gene regulatory factor X-associated ankyrin-containing protein Neighboring gene small nucleolar RNA SNORA17 Neighboring gene neurocan

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Prunotto M, et al. J Proteomics, 2013 Apr 26. PMID 23376485
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC112689

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
nuclear receptor 2C2-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001047104.2 → NP_001040569.1  nuclear receptor 2C2-associated protein isoform 1

    See identical proteins and their annotated locations for NP_001040569.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A6KA88, F7F4U7, Q4KM83
    Conserved Domains (1) summary
    cl02148
    Location:12 → 65
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination

  2. NM_001399419.1 → NP_001386348.1  nuclear receptor 2C2-associated protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    UniProtKB/TrEMBL
    A0A8I6AI65
    Related
    ENSRNOP00000092769.1, ENSRNOT00000100734.2
    Conserved Domains (1) summary
    cl02148
    Location:12 → 65
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination

  3. NM_001399420.1 → NP_001386349.1  nuclear receptor 2C2-associated protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016

  4. NM_001399421.1 → NP_001386350.1  nuclear receptor 2C2-associated protein isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000016
    Related
    ENSRNOP00000056763.3, ENSRNOT00000060012.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    19322395..19324912 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063275508.1 → XP_063131578.1  nuclear receptor 2C2-associated protein isoform X1

    UniProtKB/TrEMBL
    A0A8I6AI65
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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