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Tpgs2 tubulin polyglutamylase complex subunit 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361301, updated on 2-Nov-2024

Summary

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Official Symbol
Tpgs2provided by RGD
Official Full Name
tubulin polyglutamylase complex subunit 2provided by RGD
Primary source
RGD:1310571
See related
EnsemblRapid:ENSRNOG00000054118 AllianceGenome:RGD:1310571
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pgs2; RGD1310571
Summary
Predicted to be involved in protein polyglutamylation. Predicted to be located in centriolar satellite; cytoplasm; and microtubule. Orthologous to human TPGS2 (tubulin polyglutamylase complex subunit 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 122.6), Brain (RPKM 106.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Tpgs2 in Genome Data Viewer
Location:
18p12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (16707336..16764278, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (16432628..16489604, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (17339033..17396886, complement)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene formin homology 2 domain containing 3 Neighboring gene uncharacterized LOC134482922 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene KIAA1328 homolog Neighboring gene CUGBP, Elav-like family member 4 Neighboring gene uncharacterized LOC120098197

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in protein polyglutamylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centriolar satellite IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tubulin polyglutamylase complex subunit 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014147.1 → NP_001014169.2  tubulin polyglutamylase complex subunit 2

    See identical proteins and their annotated locations for NP_001014169.2

    Status: VALIDATED

    Source sequence(s)
    BC079332
    UniProtKB/Swiss-Prot
    Q6AXS8
    UniProtKB/TrEMBL
    A6J2L4
    Related
    ENSRNOP00000084578.1, ENSRNOT00000093690.3
    Conserved Domains (1) summary
    smart00860
    Location:43 → 192
    SMI1_KNR4; SMI1 / KNR4 family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    16707336..16764278 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096955.2 → XP_038952883.1  tubulin polyglutamylase complex subunit 2 isoform X1

    Conserved Domains (1) summary
    smart00860
    Location:2 → 133
    SMI1_KNR4; SMI1 / KNR4 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6AXS8.2 GenPept UniProtKB/Swiss-Prot:Q6AXS8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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