U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rell2 RELT-like 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361313, updated on 17-Aug-2024

Summary

Official Symbol
Rell2provided by RGD
Official Full Name
RELT-like 2provided by RGD
Primary source
RGD:1305276
See related
EnsemblRapid:ENSRNOG00000019575 AllianceGenome:RGD:1305276
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305276
Summary
Predicted to enable collagen binding activity. Predicted to be involved in positive regulation of cell-substrate adhesion and positive regulation of p38MAPK cascade. Predicted to be located in basement membrane. Orthologous to human RELL2 (RELT like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 120.9), Kidney (RPKM 34.5) and 7 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
18p11
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (30041204..30045193)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (29789996..29793986)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (31094965..31098536)

Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene diaphanous-related formin 1 Neighboring gene uncharacterized LOC120098325 Neighboring gene histone deacetylase 3 Neighboring gene FCH and double SH3 domains 1 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 Neighboring gene uncharacterized LOC134483010

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC109265

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables collagen binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in positive regulation of cell-substrate adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within positive regulation of cell-substrate adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of p38MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of p38MAPK cascade IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of p38MAPK cascade ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of p38MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in basement membrane ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular matrix ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014149.1NP_001014171.1  RELT-like protein 2

    See identical proteins and their annotated locations for NP_001014171.1

    Status: PROVISIONAL

    Source sequence(s)
    BC089946
    UniProtKB/Swiss-Prot
    Q5FVJ4
    UniProtKB/TrEMBL
    A6J3D8, A6J3D9
    Related
    ENSRNOP00000026526.3, ENSRNOT00000026526.7
    Conserved Domains (1) summary
    pfam12606
    Location:2857
    RELT; tumor necrosis factor receptor superfamily member 19

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086036.1 Reference GRCr8

    Range
    30041204..30045193
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039096962.2XP_038952890.1  RELT-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A6J3E0