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Ltv1 LTV1 ribosome biogenesis factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 361452, updated on 2-Nov-2024

Summary

Official Symbol
Ltv1provided by RGD
Official Full Name
LTV1 ribosome biogenesis factorprovided by RGD
Primary source
RGD:1311264
See related
EnsemblRapid:ENSRNOG00000015217 AllianceGenome:RGD:1311264
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311264
Summary
Predicted to be involved in ribosomal small subunit biogenesis and ribosomal small subunit export from nucleus. Predicted to be located in nucleoplasm. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in inflammatory poikiloderma with hair abnormalities and acral keratoses. Orthologous to human LTV1 (LTV1 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Muscle (RPKM 135.0), Thymus (RPKM 130.9) and 9 other tissues See more
Orthologs
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Genomic context

See Ltv1 in Genome Data Viewer
Location:
1p13
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (9385834..9398557, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (7565673..7578398, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (7323043..7335766, complement)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene keratin-associated protein 5-1-like Neighboring gene zinc finger, C2HC-type containing 1B Neighboring gene phosphatase and actin regulator 2 Neighboring gene alpha-L-fucosidase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in ribosomal small subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosomal small subunit biogenesis IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in ribosome biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of preribosome, small subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein LTV1 homolog
Names
LTV1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014157.1NP_001014179.1  protein LTV1 homolog

    See identical proteins and their annotated locations for NP_001014179.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079397
    UniProtKB/Swiss-Prot
    Q68FR7
    UniProtKB/TrEMBL
    A0A8I5ZXR8
    Related
    ENSRNOP00000020453.4, ENSRNOT00000020453.8
    Conserved Domains (1) summary
    pfam04180
    Location:15440
    LTV; Low temperature viability protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    9385834..9398557 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)