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Sertad1 SERTA domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361526, updated on 2-Nov-2024

Summary

Official Symbol
Sertad1provided by RGD
Official Full Name
SERTA domain containing 1provided by RGD
Primary source
RGD:1549778
See related
EnsemblRapid:ENSRNOG00000024363 AllianceGenome:RGD:1549778
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable transcription coactivator activity. Predicted to act upstream of or within negative regulation of cell growth and positive regulation of transcription by RNA polymerase II. Predicted to be located in sarcoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERTAD1 (SERTA domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 145.5), Lung (RPKM 144.0) and 9 other tissues See more
Orthologs
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Genomic context

See Sertad1 in Genome Data Viewer
Location:
1q21
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (91903297..91906565)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (82775692..82778961)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (84293102..84296370)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene biliverdin reductase B Neighboring gene SERTA domain containing 3 Neighboring gene periaxin Neighboring gene transmembrane protein 258, pseudogene 4 Neighboring gene homeodomain interacting protein kinase 4

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC72577

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in sarcoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
SERTA domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007735.1NP_001007736.1  SERTA domain-containing protein 1

    See identical proteins and their annotated locations for NP_001007736.1

    Status: PROVISIONAL

    Source sequence(s)
    BC061808
    UniProtKB/TrEMBL
    F7FG80, Q6P771
    Related
    ENSRNOP00000102776.1, ENSRNOT00000145758.1
    Conserved Domains (1) summary
    pfam06031
    Location:4582
    SERTA; SERTA motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    91903297..91906565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)