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Polr3e RNA polymerase III subunit E [ Rattus norvegicus (Norway rat) ]

Gene ID: 361640, updated on 28-Oct-2024

Summary

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Official Symbol
Polr3eprovided by RGD
Official Full Name
RNA polymerase III subunit Eprovided by RGD
Primary source
RGD:1308086
See related
EnsemblRapid:ENSRNOG00000016960 AllianceGenome:RGD:1308086
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308086
Summary
Predicted to be involved in tRNA transcription by RNA polymerase III. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3E (RNA polymerase III subunit E). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Adrenal (RPKM 67.8), Spleen (RPKM 58.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Polr3e in Genome Data Viewer
Location:
1q36
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (184897383..184925547)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (175466091..175494679)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (190852954..190881539)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102556194 Neighboring gene eukaryotic elongation factor-2 kinase Neighboring gene transfer RNA leucine (anticodon AAG) 1 Neighboring gene cerebellar degeneration-related protein 2 Neighboring gene small nucleolar RNA SNORA21 Neighboring gene major facilitator superfamily domain containing 13B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Cell growth- and differentiation-dependent regulation of RNA polymerase III transcription. Dumay-Odelot H, et al. Cell Cycle, 2010 Sep 15. PMID 20890107, Free PMC Article
  2. Gene duplication and neofunctionalization: POLR3G and POLR3GL. Renaud M, et al. Genome Res, 2014 Jan. PMID 24107381, Free PMC Article
  3. Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. Hu P, et al. Mol Cell Biol, 2002 Nov. PMID 12391170, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in tRNA transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase III complex ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
DNA-directed RNA polymerase III subunit RPC5
Names
RNA polymerase III polypeptide E
polymerase (RNA) III (DNA directed) polypeptide E
polymerase (RNA) III subunit E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108503.1 → NP_001101973.1  DNA-directed RNA polymerase III subunit RPC5

    See identical proteins and their annotated locations for NP_001101973.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473956
    UniProtKB/TrEMBL
    A0A8I5ZZA4, A0A8I6AND9, A6I8T2, D3ZP45
    Related
    ENSRNOP00000094486.1, ENSRNOT00000116524.2
    Conserved Domains (1) summary
    pfam04801
    Location:5 → 432
    Sin_N; Sin-like protein conserved region

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    184897383..184925547
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230168.5 → XP_006230230.1  DNA-directed RNA polymerase III subunit RPC5 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZZA4, A0A8I6AND9
    Conserved Domains (1) summary
    pfam04801
    Location:5 → 431
    Sin_N; Sin-like protein conserved region

  2. XM_039082865.2 → XP_038938793.1  DNA-directed RNA polymerase III subunit RPC5 isoform X2

    Conserved Domains (1) summary
    pfam04801
    Location:5 → 356
    Sin_N; Sin-like protein conserved region
Nucleotide Protein Strain
Heading Accession and Version

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