U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Scgb2a1 secretoglobin, family 2A, member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361725, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Symbol
Scgb2a1provided by RGD
Full Name
secretoglobin, family 2A, member 1provided by RGD
Primary source
RGD:735031
See related
EnsemblRapid:ENSRNOG00000023151 AllianceGenome:RGD:735031
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
C3.1; Psbp1; Psbpc3; Scgb2a2
Summary
Predicted to enable steroid binding activity. Predicted to be involved in androgen receptor signaling pathway. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human SCGB2A1 (secretoglobin family 2A member 1) and SCGB2A2 (secretoglobin family 2A member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 6.9), Brain (RPKM 3.0) and 7 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Scgb2a1 in Genome Data Viewer
Location:
1q43
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (215922751..215926114)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (206497848..206501211)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (225899313..225902676)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene GABA type A receptor-associated protein, pseudogene 1 Neighboring gene secretoglobin, family 1D, member 2, pseudogene 1 Neighboring gene inner centromere protein Neighboring gene 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, pseudogene 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Structural studies on rat prostatic binding protein. The primary structure of its glycosylated component C3. Peeters B, et al. Eur J Biochem, 1981 Mar 16. PMID 7014218
  2. Response elements of the androgen-regulated C3 gene. Tan J, et al. J Biol Chem, 1992 Apr 15. PMID 1339454
  3. Response elements of the androgen-regulated C3 gene. Tan JA, et al. J Biol Chem, 1992 Mar 5. PMID 1537831
  4. Sequence-specific binding of androgen-receptor complexes to prostatic binding protein genes. Claessens F, et al. Mol Cell Endocrinol, 1990 Dec 21. PMID 2095354
  5. Tissue-specific and hormonal regulation of the gene for rat prostatic steroid-binding protein in transgenic mice. Allison J, et al. Mol Cell Biol, 1989 May. PMID 2747651, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC72333

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein-containing complex binding TAS
Traceable Author Statement
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in androgen receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in androgen receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular space TAS
Traceable Author Statement
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
secretoglobin family 2A member 2
Names
androgen receptor DNA-binding domain DNA
prostatein C3 subunit
prostatein peptide C3
prostatic steroid-binding protein 1
prostatic steroid-binding protein C3
prostatic steroid-binding protein C3.2
secretoglobin, family 2A, member 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203333.2 → NP_976078.1  secretoglobin family 2A member 2 precursor

    See identical proteins and their annotated locations for NP_976078.1

    Status: VALIDATED

    Source sequence(s)
    BC062401, CB791758, JAXUCZ010000001
    UniProtKB/Swiss-Prot
    P02780, Q63463, Q9JHB9
    UniProtKB/TrEMBL
    A6HZZ8
    Related
    ENSRNOP00000037869.2, ENSRNOT00000031612.5
    Conserved Domains (1) summary
    pfam01099
    Location:1 → 91
    Uteroglobin; Uteroglobin family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    215922751..215926114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_080770.3: Suppressed sequence

    Description
    NM_080770.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P02780.1 GenPept UniProtKB/Swiss-Prot:P02780
Q9JHB9.1 GenPept UniProtKB/Swiss-Prot:Q9JHB9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools