U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nrm nurim [ Rattus norvegicus (Norway rat) ]

Gene ID: 361791, updated on 2-Nov-2024

Summary

Official Symbol
Nrmprovided by RGD
Official Full Name
nurimprovided by RGD
Primary source
RGD:1302966
See related
EnsemblRapid:ENSRNOG00000071251 AllianceGenome:RGD:1302966
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in nuclear envelope. Predicted to be active in nuclear membrane. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human NRM (nurim). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 39.8), Spleen (RPKM 28.6) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Nrm in Genome Data Viewer
Location:
20p12
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (2893126..2897725, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (2888321..2892804, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3397834..3402264, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene DEAH-box helicase 16 Neighboring gene protein phosphatase 1, regulatory subunit 18 Neighboring gene microRNA 6328 Neighboring gene mediator of DNA damage checkpoint 1 Neighboring gene tubulin, beta 5 class I

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in nuclear envelope ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear envelope ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nuclear membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
nurim
Names
nuclear envelope membrane protein
nuclear rim protein

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_212508.2NP_997673.1  nurim

    See identical proteins and their annotated locations for NP_997673.1

    Status: VALIDATED

    Source sequence(s)
    AW435457, BP490795, BP504258, DV724730
    UniProtKB/Swiss-Prot
    Q6MG14
    Related
    ENSRNOP00000001085.3, ENSRNOT00000001085.7

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    2893126..2897725 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039098800.2XP_038954728.1  nurim isoform X1

    UniProtKB/TrEMBL
    A0A0G2JZF3