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Pdxkl1 pyridoxal kinase like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361819, updated on 2-Nov-2024

Summary

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Official Symbol
Pdxkl1provided by RGD
Official Full Name
pyridoxal kinase like 1provided by RGD
Primary source
RGD:1566085
See related
EnsemblRapid:ENSRNOG00000068407 AllianceGenome:RGD:1566085
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1566085
Summary
Predicted to enable ATP binding activity; metal ion binding activity; and pyridoxal kinase activity. Predicted to be involved in phosphorylation and pyridoxal 5'-phosphate salvage. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 265.4), Liver (RPKM 55.7) and 7 other tissues See more
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Genomic context

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See Pdxkl1 in Genome Data Viewer
Location:
20p12
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (10162634..10192271, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (10162934..10192572, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (10883952..10912870, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene heat shock transcription factor 2 binding protein Neighboring gene ribosomal RNA processing 1B Neighboring gene pyridoxal kinase Neighboring gene uncharacterized LOC134483884 Neighboring gene cystatin B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in pyridoxal 5'-phosphate salvage IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
similar to pyridoxal (pyridoxine, vitamin B6) kinase
Names
pyridoxal kinase
pyridoxal kinase-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001402486.1 → NP_001389415.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000020
    UniProtKB/TrEMBL
    A0A8I6AAM1
    Related
    ENSRNOP00000090354.1, ENSRNOT00000098080.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    10162634..10192271 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039099174.2 → XP_038955102.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase isoform X1

    Conserved Domains (1) summary
    cl00192
    Location:1 → 212
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

  2. XM_039099175.2 → XP_038955103.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase isoform X2

    Conserved Domains (1) summary
    cl00192
    Location:1 → 189
    ribokinase_pfkB_like; ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, ...

  3. XM_063279232.1 → XP_063135302.1  similar to pyridoxal (pyridoxine, vitamin B6) kinase isoform X1

Nucleotide Protein Strain
Heading Accession and Version

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