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Rbms1 RNA binding motif, single stranded interacting protein 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362138, updated on 19-Jun-2024

Summary

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Official Symbol
Rbms1provided by RGD
Official Full Name
RNA binding motif, single stranded interacting protein 1provided by RGD
Primary source
RGD:1307777
See related
Ensembl:ENSRNOG00000008482 AllianceGenome:RGD:1307777
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to be involved in DNA replication. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol and nucleus. Orthologous to human RBMS1 (RNA binding motif single stranded interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Lung (RPKM 139.4), Heart (RPKM 104.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rbms1 in Genome Data Viewer
Location:
3q21
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (65604475..65829072, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (45195828..45420406, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (46802870..47025178, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene integrin subunit beta 6 Neighboring gene uncharacterized LOC108350379 Neighboring gene uncharacterized LOC134486286 Neighboring gene proteasome 26S subunit, non-ATPase 8, pseudogene 1 Neighboring gene uncharacterized LOC108352564

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(A) binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables poly(U) RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA-binding motif, single-stranded-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012184.1 → NP_001012184.1  RNA-binding motif, single-stranded-interacting protein 1

    See identical proteins and their annotated locations for NP_001012184.1

    Status: PROVISIONAL

    Source sequence(s)
    BC087094
    UniProtKB/Swiss-Prot
    Q5PQP1
    UniProtKB/TrEMBL
    A0A8L2Q545, A6HLT5
    Related
    ENSRNOP00000078893.1, ENSRNOT00000114670.1
    Conserved Domains (2) summary
    cd12470
    Location:55 → 140
    RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12474
    Location:141 → 226
    RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    65604475..65829072 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063284115.1 → XP_063140185.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X13

    UniProtKB/TrEMBL
    A0A8I5Y9I4, A0A8I5ZLN8

  2. XM_063284113.1 → XP_063140183.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A8I5Y9I4

  3. XM_063284114.1 → XP_063140184.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X12

    UniProtKB/TrEMBL
    A0A8L2Q545

  4. XM_006234237.4 → XP_006234299.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A8L2Q545
    Conserved Domains (2) summary
    cd12470
    Location:57 → 142
    RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12474
    Location:143 → 228
    RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

  5. XM_063284116.1 → XP_063140186.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X14

    UniProtKB/TrEMBL
    A0A8L2Q545

  6. XM_039105393.2 → XP_038961321.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X3

    UniProtKB/TrEMBL
    A6HLT6
    Conserved Domains (3) summary
    TIGR01645
    Location:83 → 373
    half-pint; poly-U binding splicing factor, half-pint family
    cd12470
    Location:54 → 139
    RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12473
    Location:140 → 224
    RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

  7. XM_006234235.4 → XP_006234297.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A8L2Q545
    Related
    ENSRNOP00000077414.1
    Conserved Domains (2) summary
    cd12470
    Location:55 → 140
    RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12473
    Location:141 → 225
    RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

  8. XM_006234238.5 → XP_006234300.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X8

    UniProtKB/TrEMBL
    A0A8L2Q545
    Conserved Domains (2) summary
    cd12470
    Location:57 → 142
    RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12474
    Location:143 → 228
    RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

  9. XM_006234234.5 → XP_006234296.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8L2Q545
    Conserved Domains (2) summary
    cd12470
    Location:57 → 142
    RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12474
    Location:143 → 228
    RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

  10. XM_063284117.1 → XP_063140187.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X15

    UniProtKB/TrEMBL
    A0A8I6AJP2, A0A8L2Q545

  11. XM_039105397.2 → XP_038961325.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X16

    UniProtKB/TrEMBL
    A6HLT8
    Conserved Domains (3) summary
    TIGR01645
    Location:51 → 341
    half-pint; poly-U binding splicing factor, half-pint family
    cd12470
    Location:22 → 107
    RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12473
    Location:108 → 192
    RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

  12. XM_017591893.3 → XP_017447382.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X10

    UniProtKB/TrEMBL
    A0A8L2Q545
    Related
    ENSRNOP00000011682.4

  13. XM_006234239.5 → XP_006234301.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X9

    See identical proteins and their annotated locations for XP_006234301.1

    UniProtKB/TrEMBL
    A0A8L2Q545
    Related
    ENSRNOP00000094484.1
    Conserved Domains (2) summary
    cd12470
    Location:39 → 124
    RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12474
    Location:125 → 210
    RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

  14. XM_006234241.5 → XP_006234303.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X11

    See identical proteins and their annotated locations for XP_006234303.1

    UniProtKB/TrEMBL
    A0A0G2K4R7, A6HLT7
    Conserved Domains (2) summary
    cd12470
    Location:53 → 138
    RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12473
    Location:139 → 223
    RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

  15. XM_006234236.5 → XP_006234298.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A0G2K4R7
    Related
    ENSRNOP00000073145.2
    Conserved Domains (2) summary
    cd12470
    Location:53 → 138
    RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12473
    Location:139 → 223
    RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

  16. XM_039105394.2 → XP_038961322.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A0G2K4R7
    Conserved Domains (2) summary
    cd12470
    Location:52 → 137
    RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
    cd12473
    Location:138 → 222
    RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1

  17. XM_039105398.2 → XP_038961326.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X17

    Conserved Domains (1) summary
    cl17169
    Location:1 → 38
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5PQP1.1 GenPept UniProtKB/Swiss-Prot:Q5PQP1

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