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Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit [ Rattus norvegicus (Norway rat) ]

Gene ID: 362228, updated on 10-Jul-2024

Summary

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Official Symbol
Naa20provided by RGD
Official Full Name
N(alpha)-acetyltransferase 20, NatB catalytic subunitprovided by RGD
Primary source
RGD:1307713
See related
EnsemblRapid:ENSRNOG00000010523 AllianceGenome:RGD:1307713
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Nat5
Summary
Predicted to enable peptide alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal peptidyl-methionine acetylation. Predicted to be located in cytosol and nucleus. Predicted to be part of NatB complex. Orthologous to human NAA20 (N-alpha-acetyltransferase 20, NatB catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 262.6), Heart (RPKM 256.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Naa20 in Genome Data Viewer
Location:
3q41
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (153775351..153790129)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (133322036..133336843)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (140106723..140125047)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene Ras and Rab interactor 2 Neighboring gene probable rRNA-processing protein EBP2 pseudogene Neighboring gene transfer RNA threonine (anticodon AGU) 15 Neighboring gene crooked neck pre-mRNA splicing factor 1 Neighboring gene cilia and flagella associated protein 61 Neighboring gene eukaryotic translation initiation factor 4A1, pseudogene 3 Neighboring gene INSM transcriptional repressor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. An organellar nα-acetyltransferase, naa60, acetylates cytosolic N termini of transmembrane proteins and maintains Golgi integrity. Aksnes H, et al. Cell Rep, 2015 Mar 3. PMID 25732826
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables peptide alpha-N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in N-terminal peptidyl-methionine acetylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of NatB complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NatB complex ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
N-alpha-acetyltransferase 20
Names
N-acetyltransferase 5 (ARD1 homolog, S. cerevisiae)
NP_001102065.1
XP_006235217.1
XP_063140240.1
XP_063140241.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108595.1 → NP_001102065.1  N-alpha-acetyltransferase 20

    See identical proteins and their annotated locations for NP_001102065.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474026
    UniProtKB/TrEMBL
    A6K778, B2RZ44, F7FBG0
    Conserved Domains (1) summary
    COG0456
    Location:1 → 166
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    153775351..153790129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006235155.5 → XP_006235217.1  N-alpha-acetyltransferase 20 isoform X1

    See identical proteins and their annotated locations for XP_006235217.1

    UniProtKB/TrEMBL
    A0A8I6AUK2, A6K778, A6K780
    Related
    ENSRNOP00000014047.5, ENSRNOT00000014046.8
    Conserved Domains (1) summary
    COG0456
    Location:1 → 156
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

  2. XM_063284170.1 → XP_063140240.1  N-alpha-acetyltransferase 20 isoform X2

  3. XM_063284171.1 → XP_063140241.1  N-alpha-acetyltransferase 20 isoform X3

    Related
    ENSRNOP00000097128.2, ENSRNOT00000107065.2
Nucleotide Protein Strain
Heading Accession and Version

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