Rimklb ribosomal modification protein rimK-like family member B [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Rimklbprovided by RGD
Full Name: ribosomal modification protein rimK-like family member Bprovided by RGD
Primary source: RGD:1560851
See related: EnsemblRapid:ENSRNOG00000064238 AllianceGenome:RGD:1560851
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Naags; Fam80b; RGD1560851
Summary: Predicted to enable N-acetyl-L-aspartate-L-glutamate ligase activity and citrate-L-glutamate ligase activity. Predicted to be involved in protein modification process. Predicted to be active in cytoplasm. Orthologous to human RIMKLB (ribosomal modification protein rimK like family member B). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Brain (RPKM 74.0), Testes (RPKM 67.5) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q42

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (157336950..157396970, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (155664392..155706888, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (155258241..155292809, complement)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH129465 (e-PCR)
- UniSTS:212771

UniSTS:225109 (e-PCR)
- UniSTS:225109

AI325948 (e-PCR)
- UniSTS:179455

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables N-acetyl-L-aspartate-L-glutamate ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acetyl-L-aspartate-L-glutamate ligase activity	ISO Inferred from Sequence Orthology more info
enables citrate-L-glutamate ligase activity	ISO Inferred from Sequence Orthology more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein modification process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: beta-citrylglutamate synthase B

Names: N-acetylaspartyl-glutamate synthetase; family with sequence similarity 80, member B; ribosomal protein S6 modification-like protein B

NP_001414785.1

EC 6.3.1.17

EC 6.3.2.41

XP_006237377.1

EC 6.3.1.17

EC 6.3.2.41

XP_006237378.1

EC 6.3.1.17

EC 6.3.2.41

XP_006237379.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142406.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142407.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142408.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142409.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142410.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142411.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142412.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142413.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142414.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142415.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142416.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142417.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142418.1

EC 6.3.1.17

EC 6.3.2.41

XP_063142419.1

EC 6.3.1.17

EC 6.3.2.41

XP_342750.3

EC 6.3.1.17

EC 6.3.2.41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001427856.1 → NP_001414785.1 beta-citrylglutamate synthase B

Status: VALIDATED

Source sequence(s)

JAXUCZ010000004

UniProtKB/TrEMBL

A0A8I6A4B6

Related

ENSRNOP00000085776.1, ENSRNOT00000115622.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086022.1 Reference GRCr8

Range

157336950..157396970 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063286340.1 → XP_063142410.1 beta-citrylglutamate synthase B isoform X1

UniProtKB/TrEMBL

A0A8I6A4B6
XM_063286336.1 → XP_063142406.1 beta-citrylglutamate synthase B isoform X1

UniProtKB/TrEMBL

A0A8I6A4B6
XM_063286349.1 → XP_063142419.1 beta-citrylglutamate synthase B isoform X3
XM_063286338.1 → XP_063142408.1 beta-citrylglutamate synthase B isoform X1

UniProtKB/TrEMBL

A0A8I6A4B6
XM_063286342.1 → XP_063142412.1 beta-citrylglutamate synthase B isoform X2

UniProtKB/TrEMBL

A6ILE7
XM_063286347.1 → XP_063142417.1 beta-citrylglutamate synthase B isoform X3
XM_006237316.5 → XP_006237378.1 beta-citrylglutamate synthase B isoform X1

See identical proteins and their annotated locations for XP_006237378.1

UniProtKB/TrEMBL

A0A8I6A4B6, A0A8I6A9U5

Conserved Domains (1) summary

TIGR00768
Location:8 → 303

rimK_fam; alpha-L-glutamate ligase, RimK family
XM_063286341.1 → XP_063142411.1 beta-citrylglutamate synthase B isoform X1

UniProtKB/TrEMBL

A0A8I6A4B6
XM_063286339.1 → XP_063142409.1 beta-citrylglutamate synthase B isoform X1

UniProtKB/TrEMBL

A0A8I6A4B6
XM_063286345.1 → XP_063142415.1 beta-citrylglutamate synthase B isoform X2

UniProtKB/TrEMBL

A6ILE7
XM_006237317.5 → XP_006237379.1 beta-citrylglutamate synthase B isoform X1

See identical proteins and their annotated locations for XP_006237379.1

UniProtKB/TrEMBL

A0A8I6A4B6, A0A8I6A9U5

Conserved Domains (1) summary

TIGR00768
Location:8 → 303

rimK_fam; alpha-L-glutamate ligase, RimK family
XM_063286343.1 → XP_063142413.1 beta-citrylglutamate synthase B isoform X2

UniProtKB/TrEMBL

A6ILE7
XM_063286346.1 → XP_063142416.1 beta-citrylglutamate synthase B isoform X3
XM_342749.10 → XP_342750.3 beta-citrylglutamate synthase B isoform X1

See identical proteins and their annotated locations for XP_342750.3

UniProtKB/TrEMBL

A0A8I6A4B6, A0A8I6A9U5

Conserved Domains (1) summary

TIGR00768
Location:8 → 303

rimK_fam; alpha-L-glutamate ligase, RimK family
XM_063286337.1 → XP_063142407.1 beta-citrylglutamate synthase B isoform X1

UniProtKB/TrEMBL

A0A8I6A4B6
XM_063286344.1 → XP_063142414.1 beta-citrylglutamate synthase B isoform X2

UniProtKB/TrEMBL

A6ILE7
XM_063286348.1 → XP_063142418.1 beta-citrylglutamate synthase B isoform X3
XM_006237315.4 → XP_006237377.1 beta-citrylglutamate synthase B isoform X1

See identical proteins and their annotated locations for XP_006237377.1

UniProtKB/TrEMBL

A0A8I6A4B6, A0A8I6A9U5

Conserved Domains (1) summary

TIGR00768
Location:8 → 303

rimK_fam; alpha-L-glutamate ligase, RimK family