Borcs5 BLOC-1 related complex subunit 5 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Borcs5provided by RGD
Official Full Name: BLOC-1 related complex subunit 5provided by RGD
Primary source: RGD:1307624
See related: EnsemblRapid:ENSRNOG00000006505 AllianceGenome:RGD:1307624
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Loh12cr1
Summary: Predicted to be involved in lysosome localization; organelle transport along microtubule; and positive regulation of anterograde synaptic vesicle transport. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Predicted to be part of BORC complex and plus-end kinesin complex. Predicted to be active in cytoplasmic side of lysosomal membrane and synaptic vesicle membrane. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human BORCS5 (BLOC-1 related complex subunit 5). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in Thymus (RPKM 18.5), Spleen (RPKM 18.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q43

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (169190025..169272335)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (167458640..167543556)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (168396034..168466968)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in lysosome localization	IBA Inferred from Biological aspect of Ancestor more info
involved_in lysosome localization	ISO Inferred from Sequence Orthology more info
involved_in organelle transport along microtubule	IBA Inferred from Biological aspect of Ancestor more info
involved_in organelle transport along microtubule	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of anterograde synaptic vesicle transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of BORC complex	IBA Inferred from Biological aspect of Ancestor more info
part_of BORC complex	ISO Inferred from Sequence Orthology more info
is_active_in cytoplasmic side of lysosomal membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasmic side of lysosomal membrane	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in membrane	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
part_of plus-end kinesin complex	ISO Inferred from Sequence Orthology more info
is_active_in synaptic vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: BLOC-1-related complex subunit 5

Names: loss of heterozygosity, 12, chromosomal region 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.