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Adamtsl1 ADAMTS-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362539, updated on 2-Nov-2024

Summary

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Symbol
Adamtsl1provided by RGD
Full Name
ADAMTS-like 1provided by RGD
Primary source
RGD:1306439
See related
EnsemblRapid:ENSRNOG00000006956 AllianceGenome:RGD:1306439
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
AABR07049085.1
Summary
Predicted to be involved in extracellular matrix organization. Predicted to be located in extracellular region. Orthologous to human ADAMTSL1 (ADAMTS like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Uterus (RPKM 168.3), Muscle (RPKM 45.2) and 7 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Adamtsl1 in Genome Data Viewer
Location:
5q31
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (105010471..105965792)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (99964406..100919786)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (103789443..104753866)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase A, pseudogene 11 Neighboring gene phosphoglycerate mutase 1, pseudogene 6 Neighboring gene SH3 domain containing GRB2 like 2, endophilin A1 Neighboring gene stabilizer of axonemal microtubules 1 Neighboring gene Ras-related GTP binding A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ADAMTS-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431177.1 → NP_001418106.1  ADAMTS-like protein 1 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005

  2. NM_001431178.1 → NP_001418107.1  ADAMTS-like protein 1 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/TrEMBL
    A0A1W2Q621

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    105010471..105965792
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039111084.2 → XP_038967012.1  ADAMTS-like protein 1 isoform X6

    Conserved Domains (5) summary
    smart00408
    Location:939 → 997
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:84 → 130
    TSP1; Thrombospondin type 1 repeats
    pfam19030
    Location:718 → 776
    TSP1_ADAMTS; Thrombospondin type 1 domain
    cd00096
    Location:1352 → 1356
    Ig; Ig strand B [structural motif]
    cl11960
    Location:1336 → 1418
    Ig; Immunoglobulin domain

  2. XM_039111080.2 → XP_038967008.1  ADAMTS-like protein 1 isoform X2

    Conserved Domains (5) summary
    smart00408
    Location:922 → 980
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:84 → 130
    TSP1; Thrombospondin type 1 repeats
    pfam19030
    Location:701 → 759
    TSP1_ADAMTS; Thrombospondin type 1 domain
    cd00096
    Location:1335 → 1339
    Ig; Ig strand B [structural motif]
    cl11960
    Location:1319 → 1401
    Ig; Immunoglobulin domain

  3. XM_039111079.2 → XP_038967007.1  ADAMTS-like protein 1 isoform X1

    UniProtKB/TrEMBL
    F1LWA1
    Related
    ENSRNOP00000055317.5, ENSRNOT00000058520.7
    Conserved Domains (6) summary
    smart00408
    Location:939 → 997
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:84 → 130
    TSP1; Thrombospondin type 1 repeats
    pfam08686
    Location:1778 → 1807
    PLAC; PLAC (protease and lacunin) domain
    pfam19030
    Location:718 → 776
    TSP1_ADAMTS; Thrombospondin type 1 domain
    cd00096
    Location:1352 → 1356
    Ig; Ig strand B [structural motif]
    cl11960
    Location:1336 → 1418
    Ig; Immunoglobulin domain

  4. XM_039111081.2 → XP_038967009.1  ADAMTS-like protein 1 isoform X3

    Conserved Domains (5) summary
    smart00408
    Location:891 → 949
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:36 → 82
    TSP1; Thrombospondin type 1 repeats
    pfam19030
    Location:670 → 728
    TSP1_ADAMTS; Thrombospondin type 1 domain
    cd00096
    Location:1304 → 1308
    Ig; Ig strand B [structural motif]
    cl11960
    Location:1288 → 1370
    Ig; Immunoglobulin domain

  5. XM_039111082.2 → XP_038967010.1  ADAMTS-like protein 1 isoform X4

    Related
    ENSRNOP00000076109.2, ENSRNOT00000093462.3
    Conserved Domains (6) summary
    smart00408
    Location:891 → 949
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:36 → 82
    TSP1; Thrombospondin type 1 repeats
    pfam08686
    Location:1730 → 1759
    PLAC; PLAC (protease and lacunin) domain
    pfam19030
    Location:670 → 728
    TSP1_ADAMTS; Thrombospondin type 1 domain
    cd00096
    Location:1304 → 1308
    Ig; Ig strand B [structural motif]
    cl11960
    Location:1288 → 1370
    Ig; Immunoglobulin domain

  6. XM_039111083.2 → XP_038967011.1  ADAMTS-like protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A1W2Q6M9
    Related
    ENSRNOP00000076311.2, ENSRNOT00000093557.3
    Conserved Domains (6) summary
    smart00408
    Location:874 → 932
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:36 → 82
    TSP1; Thrombospondin type 1 repeats
    pfam08686
    Location:1713 → 1742
    PLAC; PLAC (protease and lacunin) domain
    pfam19030
    Location:653 → 711
    TSP1_ADAMTS; Thrombospondin type 1 domain
    cd00096
    Location:1287 → 1291
    Ig; Ig strand B [structural motif]
    cl11960
    Location:1271 → 1353
    Ig; Immunoglobulin domain

  7. XM_039111086.2 → XP_038967014.1  ADAMTS-like protein 1 isoform X7

    Conserved Domains (4) summary
    smart00408
    Location:423 → 481
    IGc2; Immunoglobulin C-2 Type
    pfam19030
    Location:202 → 260
    TSP1_ADAMTS; Thrombospondin type 1 domain
    cd00096
    Location:836 → 840
    Ig; Ig strand B [structural motif]
    cl11960
    Location:820 → 902
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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