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Bend5 BEN domain containing 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362564, updated on 2-Nov-2024

Summary

Official Symbol
Bend5provided by RGD
Official Full Name
BEN domain containing 5provided by RGD
Primary source
RGD:1584958
See related
EnsemblRapid:ENSRNOG00000008025 AllianceGenome:RGD:1584958
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in Golgi apparatus. Orthologous to human BEND5 (BEN domain containing 5). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 102.2), Spleen (RPKM 73.7) and 7 other tissues See more
Orthologs
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Genomic context

See Bend5 in Genome Data Viewer
Location:
5q35
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (131519214..131565228)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (126290648..126336662)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (131257127..131312335)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene DMRT-like family A2 Neighboring gene ELAV like RNA binding protein 4 Neighboring gene AGBL carboxypeptidase 4 Neighboring gene spermatogenesis associated 6 Neighboring gene solute carrier family 5 member 9

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
 
involved_in protein side chain deglutamylation IEA
Inferred from Electronic Annotation
more info
 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in axon cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
BEN domain-containing protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108672.1NP_001102142.1  BEN domain-containing protein 5

    See identical proteins and their annotated locations for NP_001102142.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474008
    UniProtKB/TrEMBL
    A6JZ07, D3ZQP2
    Related
    ENSRNOP00000010628.6, ENSRNOT00000010628.9
    Conserved Domains (1) summary
    pfam10523
    Location:323397
    BEN; BEN domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    131519214..131565228
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)