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Nipal2 NIPA-like domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362899, updated on 2-Nov-2024

Summary

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Official Symbol
Nipal2provided by RGD
Official Full Name
NIPA-like domain containing 2provided by RGD
Primary source
RGD:1564315
See related
EnsemblRapid:ENSRNOG00000005190 AllianceGenome:RGD:1564315
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Npal2; RGD1564315
Summary
Predicted to enable magnesium ion transmembrane transporter activity. Predicted to be involved in magnesium ion transport. Predicted to be active in membrane. Orthologous to human NIPAL2 (NIPA like domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Lung (RPKM 143.7), Heart (RPKM 82.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Nipal2 in Genome Data Viewer
Location:
7q22
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (67659628..67771105, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (65774477..65884807, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (73339706..73450262, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene POP1 homolog, ribonuclease P/MRP subunit Neighboring gene uncharacterized LOC120093631 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene uncharacterized LOC134479710 Neighboring gene uncharacterized LOC134479602

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables magnesium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in magnesium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in magnesium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
NIPA-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130559.1 → NP_001124031.1  NIPA-like protein 2

    See identical proteins and their annotated locations for NP_001124031.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473950
    UniProtKB/TrEMBL
    A0A8I6AE26, A6HR07, D3ZKE2
    Related
    ENSRNOP00000006943.6, ENSRNOT00000006943.7
    Conserved Domains (1) summary
    pfam05653
    Location:45 → 331
    Mg_trans_NIPA; Magnesium transporter NIPA

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    67659628..67771105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063263832.1 → XP_063119902.1  NIPA-like protein 2 isoform X1

    UniProtKB/TrEMBL
    A6HR07, D3ZKE2

  2. XM_006241544.5 → XP_006241606.1  NIPA-like protein 2 isoform X2

    Conserved Domains (1) summary
    cl23754
    Location:45 → 256
    EamA; EamA-like transporter family

  3. XM_039079513.2 → XP_038935441.1  NIPA-like protein 2 isoform X3

    Conserved Domains (1) summary
    cl23754
    Location:8 → 149
    EamA; EamA-like transporter family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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