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Lrrc24 leucine rich repeat containing 24 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362945, updated on 10-Jul-2024

Summary

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Official Symbol
Lrrc24provided by RGD
Official Full Name
leucine rich repeat containing 24provided by RGD
Primary source
RGD:1308720
See related
EnsemblRapid:ENSRNOG00000016204 AllianceGenome:RGD:1308720
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1308720
Summary
Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. Orthologous to human LRRC24 (leucine rich repeat containing 24). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Brain (RPKM 46.0), Kidney (RPKM 18.4) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Lrrc24 in Genome Data Viewer
Location:
7q34
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (110317935..110325201, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108437296..108444561, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117779733..117786872, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 3 Neighboring gene RecQ like helicase 4 Neighboring gene leucine rich repeat containing 14 Neighboring gene similar to human chromosome 8 open reading frame 82 Neighboring gene Rho GTPase activating protein 39 Neighboring gene uncharacterized LOC134479930

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins. Um JW, et al. Cell Rep, 2014 Mar 27. PMID 24613359, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of synapse assembly ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135896.1 → NP_001129368.1  leucine-rich repeat-containing protein 24 precursor

    See identical proteins and their annotated locations for NP_001129368.1

    Status: PROVISIONAL

    Source sequence(s)
    BC127521
    UniProtKB/TrEMBL
    A0JPN8
    Conserved Domains (6) summary
    TIGR00864
    Location:188 → 259
    PCC; polycystin cation channel protein
    sd00033
    Location:61 → 83
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:84 → 142
    LRR_8; Leucine rich repeat
    pfam13927
    Location:267 → 357
    Ig_3; Immunoglobulin domain
    cd00096
    Location:267 → 271
    Ig; Ig strand A [structural motif]
    cd21340
    Location:63 → 212
    PPP1R42; protein phosphatase 1 regulatory subunit 42

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    110317935..110325201 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008765581.4 → XP_008763803.1  leucine-rich repeat-containing protein 24 isoform X1

    See identical proteins and their annotated locations for XP_008763803.1

    UniProtKB/TrEMBL
    A0JPN8
    Conserved Domains (6) summary
    TIGR00864
    Location:188 → 259
    PCC; polycystin cation channel protein
    sd00033
    Location:61 → 83
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:84 → 142
    LRR_8; Leucine rich repeat
    pfam13927
    Location:267 → 357
    Ig_3; Immunoglobulin domain
    cd00096
    Location:267 → 271
    Ig; Ig strand A [structural motif]
    cd21340
    Location:63 → 212
    PPP1R42; protein phosphatase 1 regulatory subunit 42

  2. XM_039079560.2 → XP_038935488.1  leucine-rich repeat-containing protein 24 isoform X1

    UniProtKB/TrEMBL
    A0JPN8
    Related
    ENSRNOP00000029554.5, ENSRNOT00000030517.7
    Conserved Domains (6) summary
    TIGR00864
    Location:188 → 259
    PCC; polycystin cation channel protein
    sd00033
    Location:61 → 83
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:84 → 142
    LRR_8; Leucine rich repeat
    pfam13927
    Location:267 → 357
    Ig_3; Immunoglobulin domain
    cd00096
    Location:267 → 271
    Ig; Ig strand A [structural motif]
    cd21340
    Location:63 → 212
    PPP1R42; protein phosphatase 1 regulatory subunit 42
Nucleotide Protein Strain
Heading Accession and Version

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