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Zbtb44 zinc finger and BTB domain containing 44 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363035, updated on 28-Oct-2024

Summary

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Official Symbol
Zbtb44provided by RGD
Official Full Name
zinc finger and BTB domain containing 44provided by RGD
Primary source
RGD:1308984
See related
EnsemblRapid:ENSRNOG00000005578 AllianceGenome:RGD:1308984
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Btbd15; RGD1308984
Summary
Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Orthologous to human ZBTB44 (zinc finger and BTB domain containing 44). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Biased expression in Thymus (RPKM 121.6), Muscle (RPKM 119.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zbtb44 in Genome Data Viewer
Location:
8q13
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (37724237..37782220)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (29466055..29524027)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (32165388..32223341)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene small ubiquitin-related modifier 2-like Neighboring gene ST14 transmembrane serine protease matriptase Neighboring gene amyloid beta precursor like protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC125242

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger and BTB domain-containing protein 44
Names
BTB (POZ) domain containing 15
BTB/POZ domain-containing protein 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001034942.2 → NP_001030114.1  zinc finger and BTB domain-containing protein 44

    See identical proteins and their annotated locations for NP_001030114.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    Q3SWU4
    UniProtKB/TrEMBL
    A0A0G2JVS3, A6JYF7
    Related
    ENSRNOP00000084481.1, ENSRNOT00000100746.2
    Conserved Domains (5) summary
    PRK10049
    Location:203 → 322
    pgaA; outer membrane protein PgaA; Provisional
    sd00017
    Location:401 → 421
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18228
    Location:15 → 130
    BTB_POZ_ZBTB44; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 44 (ZBTB44)
    pfam00096
    Location:399 → 421
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:413 → 438
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    37724237..37782220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063265734.1 → XP_063121804.1  zinc finger and BTB domain-containing protein 44 isoform X4

  2. XM_063265733.1 → XP_063121803.1  zinc finger and BTB domain-containing protein 44 isoform X4

  3. XM_006242769.5 → XP_006242831.1  zinc finger and BTB domain-containing protein 44 isoform X2

    Conserved Domains (7) summary
    smart00225
    Location:32 → 128
    BTB; Broad-Complex, Tramtrack and Bric a brac
    COG5048
    Location:351 → 431
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:383 → 403
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:471 → 493
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:381 → 403
    zf-C2H2; Zinc finger, C2H2 type
    pfam00651
    Location:21 → 125
    BTB; BTB/POZ domain
    pfam13465
    Location:395 → 420
    zf-H2C2_2; Zinc-finger double domain

  4. XM_006242768.5 → XP_006242830.1  zinc finger and BTB domain-containing protein 44 isoform X1

    UniProtKB/TrEMBL
    A0A8L2Q3C2
    Related
    ENSRNOP00000007539.6, ENSRNOT00000007539.8
    Conserved Domains (7) summary
    smart00225
    Location:32 → 128
    BTB; Broad-Complex, Tramtrack and Bric a brac
    COG5048
    Location:383 → 449
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:401 → 421
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00020
    Location:489 → 511
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:399 → 421
    zf-C2H2; Zinc finger, C2H2 type
    pfam00651
    Location:21 → 125
    BTB; BTB/POZ domain
    pfam13465
    Location:413 → 438
    zf-H2C2_2; Zinc-finger double domain

  5. XM_063265731.1 → XP_063121801.1  zinc finger and BTB domain-containing protein 44 isoform X3

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3SWU4.1 GenPept UniProtKB/Swiss-Prot:Q3SWU4

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