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Plet1 placenta expressed transcript 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363060, updated on 10-Jul-2024

Summary

Official Symbol
Plet1provided by RGD
Official Full Name
placenta expressed transcript 1provided by RGD
Primary source
RGD:1359217
See related
EnsemblRapid:ENSRNOG00000024346 AllianceGenome:RGD:1359217
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in negative regulation of cell-matrix adhesion; positive regulation of cell migration; and wound healing, spreading of epidermal cells. Predicted to be anchored component of membrane. Predicted to be active in apical plasma membrane and external side of plasma membrane. Orthologous to human PLET1 (placenta expressed transcript 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Uterus (RPKM 399.3), Testes (RPKM 349.0) and 4 other tissues See more
Orthologs
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Genomic context

See Plet1 in Genome Data Viewer
Location:
8q23
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (59738639..59750062)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (50842242..50853666)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (54925624..54937068)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094147 Neighboring gene phosphoglycerate mutase 1, pseudogene 13 Neighboring gene 6-pyruvoyl-tetrahydropterin synthase Neighboring gene beta-carotene oxygenase 2 Neighboring gene interleukin 18

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in negative regulation of cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in negative regulation of cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of cell-matrix adhesion ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in wound healing, spreading of epidermal cells IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in wound healing, spreading of epidermal cells ISO
Inferred from Sequence Orthology
more info
 
involved_in wound healing, spreading of epidermal cells ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
is_active_in apical plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in apical plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
placenta-expressed transcript 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014209.2NP_001014231.1  placenta-expressed transcript 1 protein isoform 1 precursor

    See identical proteins and their annotated locations for NP_001014231.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    Q5HZW7
    UniProtKB/TrEMBL
    A0A8L2QTA5
    Related
    ENSRNOP00000055980.4, ENSRNOT00000059210.6
  2. NM_001393867.1NP_001380796.1  placenta-expressed transcript 1 protein isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A0A8L2QTA5, A6J4D2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    59738639..59750062
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)