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INPP4A inositol polyphosphate-4-phosphatase type I A [ Homo sapiens (human) ]

Gene ID: 3631, updated on 2-Nov-2024

Summary

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Official Symbol
INPP4Aprovided by HGNC
Official Full Name
inositol polyphosphate-4-phosphatase type I Aprovided by HGNC
Primary source
HGNC:HGNC:6074
See related
Ensembl:ENSG00000040933 MIM:600916; AllianceGenome:HGNC:6074
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
INPP4; TVAS1
Summary
This gene encodes an Mg++ independent enzyme that hydrolyzes the 4-position phosphate from the inositol ring of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and inositol 3,4-bisphosphate. Multiple transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Aug 2008]
Expression
Ubiquitous expression in brain (RPKM 6.3), spleen (RPKM 4.2) and 24 other tissues See more
Orthologs
mouse all
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Genomic context

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See INPP4A in Genome Data Viewer
Location:
2q11.2
Exon count:
35
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (98444587..98594392)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (98902886..99052718)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (99061050..99210855)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene von Willebrand factor A domain containing 3B Neighboring gene ATP synthase F1 subunit beta pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:98896664-98897164 Neighboring gene NANOG hESC enhancer GRCh37_chr2:98933593-98934329 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr2:98950857-98951787 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:98963419-98963930 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:98993983-98994750 Neighboring gene Sharpr-MPRA regulatory region 13649 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:98998693-98999270 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr2:98999847-99000424 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:99000425-99001000 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:99004561-99004748 Neighboring gene cyclic nucleotide gated channel subunit alpha 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16257 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr2:99051832-99053031 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16258 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11800 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16259 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16260 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:99079757-99080272 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16262 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16261 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16263 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:99082317-99082881 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11801 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16264 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16265 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16266 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16267 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:99136086-99136586 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:99136587-99137087 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16268 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:99170837-99171337 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:99176784-99176955 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:99190711-99190893 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:99200423-99200924 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:99209219-99209372 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 16269 Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:99224127-99225116 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 11802 Neighboring gene cytochrome c oxidase assembly factor 5 Neighboring gene unc-50 inner nuclear membrane RNA binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Hindbrain malformation and myoclonic seizures associated with a deleterious mutation in the INPP4A gene. Sheffer R, et al. Neurogenetics, 2015 Jan. PMID 25338135
  2. A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma. Sharma M, et al. Am J Respir Crit Care Med, 2008 Apr 1. PMID 18187694
  3. Secretory Inositol Polyphosphate 4-Phosphatase Protects against Airway Inflammation and Remodeling. Khanna K, et al. Am J Respir Cell Mol Biol, 2019 Apr. PMID 30335467, Free PMC Article
  4. Assignment of the inositol polyphosphate 4-phosphatase type I gene (INPP4A) to human chromosome band 2q11.2 by in situ hybridization. Joseph RE, et al. Cytogenet Cell Genet, 1999. PMID 10702694
  5. Whole exome sequencing identified a novel nonsense INPP4A mutation in a family with intellectual disability. Banihashemi S, et al. Eur J Med Genet, 2020 Apr. PMID 31978615

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Deficiency of INPP4A promotes M2 macrophage polarization in eosinophilic chronic rhinosinusitis with nasal polyps.
    Title: Deficiency of INPP4A promotes M2 macrophage polarization in eosinophilic chronic rhinosinusitis with nasal polyps.
  2. Whole exome sequencing identified a novel nonsense INPP4A mutation in a family with intellectual disability.
    Title: Whole exome sequencing identified a novel nonsense INPP4A mutation in a family with intellectual disability.
  3. miR-935 Inhibits Oral Squamous Cell Carcinoma and Targets Inositol Polyphosphate-4-phosphatase Type IA (INPP4A).
    Title: miR-935 Inhibits Oral Squamous Cell Carcinoma and Targets Inositol Polyphosphate-4-phosphatase Type IA (INPP4A).
  4. Low INPP4A expression is associated with cell proliferation, migration, and invasion in colorectal cancer.
    Title: MicroRNA-935 acts as a prognostic marker and promotes cell proliferation, migration, and invasion in colorectal cancer.
  5. INPP4A is secreted by airway epithelial cells and extracellular INPP4A critically inhibits airway inflammation and remodeling.
    Title: Secretory Inositol Polyphosphate 4-Phosphatase Protects against Airway Inflammation and Remodeling.
  6. INPP4A could possibly serve as a candidate gene for alterations associated with asbestos exposure.
    Title: Driver Gene and Novel Mutations in Asbestos-Exposed Lung Adenocarcinoma and Malignant Mesothelioma Detected by Exome Sequencing.
  7. Data adds a new etiology to the spectrum of hindbrain malformations in human, and when presented with myoclonic epilepsy may lead to the clinical suspicion of INPP4A defect.
    Title: Hindbrain malformation and myoclonic seizures associated with a deleterious mutation in the INPP4A gene.
  8. INPP4A represents the first signalling protein with a function in neurons to suppress excitotoxic cell death
    Title: The PtdIns(3,4)P(2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death.
  9. The +110832A/G (Thr/Ala) variant of INPP4A was significantly associated with asthma in an Indian population.
    Title: A genetic variation in inositol polyphosphate 4 phosphatase a enhances susceptibility to asthma.
  10. Observational study of gene-disease association. (HuGE Navigator)
    Title: Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.
Submit: New GeneRIF Correction See all GeneRIFs (11)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association of mood-incongruent psychotic bipolar disorder.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables inositol-1,3,4-trisphosphate 4-phosphatase activity TAS
Traceable Author Statement
more info
  
enables inositol-3,4-bisphosphate 4-phosphatase activity TAS
Traceable Author Statement
more info
  
enables phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity TAS
Traceable Author Statement
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in inositol phosphate metabolic process TAS
Traceable Author Statement
more info
  
involved_in phosphatidylinositol biosynthetic process TAS
Traceable Author Statement
more info
  
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in early endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear membrane IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in postsynaptic density ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in recycling endosome membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
inositol polyphosphate-4-phosphatase type I A
Names
inositol polyphosphate-4-phosphatase, type I, 107kD
inositol polyphosphate-4-phosphatase, type I, 107kDa
type I inositol 3,4-bisphosphate 4-phosphatase
NP_001127696.1
NP_001127697.1
NP_001338353.1
NP_001338354.1
NP_001338355.1
NP_001338356.1
NP_001338357.1
NP_001338358.1
NP_001557.1
NP_004018.1
XP_006712562.1
XP_006712563.1
XP_006712564.1
XP_006712565.1
XP_006712566.1
XP_006712568.1
XP_006712569.1
XP_011509424.1
XP_011509425.1
XP_011509426.1
XP_011509427.1
XP_011509429.1
XP_016859483.1
XP_016859489.1
XP_016859490.1
XP_024308644.1
XP_047300154.1
XP_047300155.1
XP_047300156.1
XP_047300157.1
XP_047300159.1
XP_047300160.1
XP_047300161.1
XP_047300162.1
XP_047300163.1
XP_047300165.1
XP_047300166.1
XP_047300167.1
XP_047300168.1
XP_047300169.1
XP_047300170.1
XP_047300171.1
XP_047300173.1
XP_047300174.1
XP_054197813.1
XP_054197814.1
XP_054197815.1
XP_054197816.1
XP_054197817.1
XP_054197818.1
XP_054197819.1
XP_054197820.1
XP_054197821.1
XP_054197822.1
XP_054197823.1
XP_054197824.1
XP_054197825.1
XP_054197826.1
XP_054197827.1
XP_054197828.1
XP_054197829.1
XP_054197830.1
XP_054197831.1
XP_054197832.1
XP_054197833.1
XP_054197834.1
XP_054197835.1
XP_054197836.1
XP_054197837.1
XP_054197838.1
XP_054197839.1
XP_054197840.1
XP_054197841.1
XP_054197842.1
XP_054197843.1
XP_054197844.1
XP_054197845.1
XP_054197846.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029890.2 RefSeqGene

    Range
    5273..154807
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001134224.2 → NP_001127696.1  inositol polyphosphate-4-phosphatase type I A isoform d

    See identical proteins and their annotated locations for NP_001127696.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (d) uses an alternate, in-frame splice site in the coding region compared to variant a. The resulting isoform (d) is longer but has the same N- and C-termini compared to isoform a.
    Source sequence(s)
    AC010134, AF368319, BC028361
    Consensus CDS
    CCDS46369.1
    UniProtKB/Swiss-Prot
    O15326, Q13187, Q53TD8, Q8TC02, Q96PE3
    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000427722.1, ENST00000523221.2
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  2. NM_001134225.2 → NP_001127697.1  inositol polyphosphate-4-phosphatase type I A isoform c

    See identical proteins and their annotated locations for NP_001127697.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (c) lacks an alternate exon and uses an alternate, in-frame splice site in the coding region compared to variant a. The resulting isoform (c) is longer but has the same N- and C-termini compared to isoform a.
    Source sequence(s)
    AC010134, BC028361
    Consensus CDS
    CCDS46371.1
    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000386777.4, ENST00000409851.8
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  3. NM_001351424.1 → NP_001338353.1  inositol polyphosphate-4-phosphatase type I A isoform e

    Status: REVIEWED

    Source sequence(s)
    AC010134
    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  4. NM_001351425.2 → NP_001338354.1  inositol polyphosphate-4-phosphatase type I A isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (f), as well as variant g, encodes isoform f.
    Source sequence(s)
    AC010134
    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000520526.1, ENST00000715854.1
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  5. NM_001351426.2 → NP_001338355.1  inositol polyphosphate-4-phosphatase type I A isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (g), as well as variant f, encodes isoform f.
    Source sequence(s)
    AC010134
    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000520533.1, ENST00000715898.1
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  6. NM_001351427.2 → NP_001338356.1  inositol polyphosphate-4-phosphatase type I A isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (h), as well as variant a, encodes isoform a.
    Source sequence(s)
    AC010134
    Consensus CDS
    CCDS46370.1
    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  7. NM_001351428.2 → NP_001338357.1  inositol polyphosphate-4-phosphatase type I A isoform g

    Status: REVIEWED

    Source sequence(s)
    AC010134
    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000520532.1, ENST00000715897.1
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  8. NM_001351429.2 → NP_001338358.1  inositol polyphosphate-4-phosphatase type I A isoform h

    Status: REVIEWED

    Source sequence(s)
    AC010134
    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  9. NM_001566.2 → NP_001557.1  inositol polyphosphate-4-phosphatase type I A isoform b

    See identical proteins and their annotated locations for NP_001557.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (b) contains an alternate exon in the 3' coding region and uses a different stop codon compared to variant a. The resulting isoform (b) is longer and has a distint C-terminus compared to isoform a.
    Source sequence(s)
    AC010134, BC028361, U96919
    Consensus CDS
    CCDS46372.1
    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000387294.3, ENST00000409540.7
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  10. NM_004027.3 → NP_004018.1  inositol polyphosphate-4-phosphatase type I A isoform a

    See identical proteins and their annotated locations for NP_004018.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (a) encodes the shortest isoform (a). Variants a and h both encode the same isoform (a).
    Source sequence(s)
    AC010134, BC028361, U26398
    Consensus CDS
    CCDS46370.1
    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000386704.3, ENST00000409016.8
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    98444587..98594392
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047444199.1 → XP_047300155.1  inositol polyphosphate-4-phosphatase type I A isoform X8

  2. XM_047444209.1 → XP_047300165.1  inositol polyphosphate-4-phosphatase type I A isoform X19

  3. XM_047444204.1 → XP_047300160.1  inositol polyphosphate-4-phosphatase type I A isoform X11

  4. XM_024452876.2 → XP_024308644.1  inositol polyphosphate-4-phosphatase type I A isoform X1

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  5. XM_006712503.4 → XP_006712566.1  inositol polyphosphate-4-phosphatase type I A isoform X6

    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000520525.1, ENST00000715853.1
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  6. XM_047444200.1 → XP_047300156.1  inositol polyphosphate-4-phosphatase type I A isoform X9

  7. XM_017004000.2 → XP_016859489.1  inositol polyphosphate-4-phosphatase type I A isoform X21

    UniProtKB/TrEMBL
    A0A9L9PY55
    Related
    ENSP00000520534.1, ENST00000715899.1
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  8. XM_047444201.1 → XP_047300157.1  inositol polyphosphate-4-phosphatase type I A isoform X10

  9. XM_011511124.3 → XP_011509426.1  inositol polyphosphate-4-phosphatase type I A isoform X19

    See identical proteins and their annotated locations for XP_011509426.1

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  10. XM_017004001.2 → XP_016859490.1  inositol polyphosphate-4-phosphatase type I A isoform X22

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  11. XM_047444203.1 → XP_047300159.1  inositol polyphosphate-4-phosphatase type I A isoform X11

  12. XM_047444211.1 → XP_047300167.1  inositol polyphosphate-4-phosphatase type I A isoform X23

  13. XM_006712505.4 → XP_006712568.1  inositol polyphosphate-4-phosphatase type I A isoform X14

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  14. XM_047444206.1 → XP_047300162.1  inositol polyphosphate-4-phosphatase type I A isoform X17

  15. XM_047444210.1 → XP_047300166.1  inositol polyphosphate-4-phosphatase type I A isoform X20

  16. XM_047444214.1 → XP_047300170.1  inositol polyphosphate-4-phosphatase type I A isoform X26

  17. XM_047444205.1 → XP_047300161.1  inositol polyphosphate-4-phosphatase type I A isoform X15

  18. XM_006712499.4 → XP_006712562.1  inositol polyphosphate-4-phosphatase type I A isoform X1

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  19. XM_006712502.4 → XP_006712565.1  inositol polyphosphate-4-phosphatase type I A isoform X4

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  20. XM_006712506.4 → XP_006712569.1  inositol polyphosphate-4-phosphatase type I A isoform X16

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  21. XM_006712500.4 → XP_006712563.1  inositol polyphosphate-4-phosphatase type I A isoform X2

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  22. XM_006712501.4 → XP_006712564.1  inositol polyphosphate-4-phosphatase type I A isoform X3

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  23. XM_047444198.1 → XP_047300154.1  inositol polyphosphate-4-phosphatase type I A isoform X7

  24. XM_017003994.2 → XP_016859483.1  inositol polyphosphate-4-phosphatase type I A isoform X13

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  25. XM_047444207.1 → XP_047300163.1  inositol polyphosphate-4-phosphatase type I A isoform X18

  26. XM_011511122.3 → XP_011509424.1  inositol polyphosphate-4-phosphatase type I A isoform X5

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cl14603
    Location:32 → 142
    C2; C2 domain

  27. XM_011511123.3 → XP_011509425.1  inositol polyphosphate-4-phosphatase type I A isoform X12

    UniProtKB/TrEMBL
    A0A9L9PY55
    Conserved Domains (1) summary
    cd04048
    Location:44 → 157
    C2A_Copine; C2 domain first repeat in Copine

  28. XM_047444212.1 → XP_047300168.1  inositol polyphosphate-4-phosphatase type I A isoform X24

  29. XM_047444213.1 → XP_047300169.1  inositol polyphosphate-4-phosphatase type I A isoform X25

  30. XM_047444215.1 → XP_047300171.1  inositol polyphosphate-4-phosphatase type I A isoform X27

  31. XM_011511125.3 → XP_011509427.1  inositol polyphosphate-4-phosphatase type I A isoform X28

    UniProtKB/TrEMBL
    A0A9L9PY55

  32. XM_047444217.1 → XP_047300173.1  inositol polyphosphate-4-phosphatase type I A isoform X29

  33. XM_047444218.1 → XP_047300174.1  inositol polyphosphate-4-phosphatase type I A isoform X31

  34. XM_011511127.3 → XP_011509429.1  inositol polyphosphate-4-phosphatase type I A isoform X30

RNA

  1. XR_922915.3 RNA Sequence

  2. XR_007074203.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    98902886..99052718
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054341846.1 → XP_054197821.1  inositol polyphosphate-4-phosphatase type I A isoform X8

  2. XM_054341850.1 → XP_054197825.1  inositol polyphosphate-4-phosphatase type I A isoform X11

  3. XM_054341839.1 → XP_054197814.1  inositol polyphosphate-4-phosphatase type I A isoform X1

  4. XM_054341844.1 → XP_054197819.1  inositol polyphosphate-4-phosphatase type I A isoform X6

  5. XM_054341847.1 → XP_054197822.1  inositol polyphosphate-4-phosphatase type I A isoform X9

  6. XM_054341861.1 → XP_054197836.1  inositol polyphosphate-4-phosphatase type I A isoform X21

  7. XM_054341848.1 → XP_054197823.1  inositol polyphosphate-4-phosphatase type I A isoform X10

  8. XM_054341859.1 → XP_054197834.1  inositol polyphosphate-4-phosphatase type I A isoform X19

  9. XM_054341862.1 → XP_054197837.1  inositol polyphosphate-4-phosphatase type I A isoform X22

  10. XM_054341849.1 → XP_054197824.1  inositol polyphosphate-4-phosphatase type I A isoform X11

  11. XM_054341863.1 → XP_054197838.1  inositol polyphosphate-4-phosphatase type I A isoform X23

  12. XM_054341853.1 → XP_054197828.1  inositol polyphosphate-4-phosphatase type I A isoform X14

  13. XM_054341854.1 → XP_054197829.1  inositol polyphosphate-4-phosphatase type I A isoform X14

  14. XM_054341857.1 → XP_054197832.1  inositol polyphosphate-4-phosphatase type I A isoform X17

  15. XM_054341860.1 → XP_054197835.1  inositol polyphosphate-4-phosphatase type I A isoform X20

  16. XM_054341866.1 → XP_054197841.1  inositol polyphosphate-4-phosphatase type I A isoform X26

  17. XM_054341855.1 → XP_054197830.1  inositol polyphosphate-4-phosphatase type I A isoform X15

  18. XM_054341838.1 → XP_054197813.1  inositol polyphosphate-4-phosphatase type I A isoform X1

  19. XM_054341842.1 → XP_054197817.1  inositol polyphosphate-4-phosphatase type I A isoform X4

  20. XM_054341856.1 → XP_054197831.1  inositol polyphosphate-4-phosphatase type I A isoform X16

  21. XM_054341840.1 → XP_054197815.1  inositol polyphosphate-4-phosphatase type I A isoform X2

  22. XM_054341841.1 → XP_054197816.1  inositol polyphosphate-4-phosphatase type I A isoform X3

  23. XM_054341845.1 → XP_054197820.1  inositol polyphosphate-4-phosphatase type I A isoform X7

  24. XM_054341852.1 → XP_054197827.1  inositol polyphosphate-4-phosphatase type I A isoform X13

  25. XM_054341858.1 → XP_054197833.1  inositol polyphosphate-4-phosphatase type I A isoform X18

  26. XM_054341843.1 → XP_054197818.1  inositol polyphosphate-4-phosphatase type I A isoform X5

  27. XM_054341851.1 → XP_054197826.1  inositol polyphosphate-4-phosphatase type I A isoform X12

  28. XM_054341864.1 → XP_054197839.1  inositol polyphosphate-4-phosphatase type I A isoform X24

  29. XM_054341865.1 → XP_054197840.1  inositol polyphosphate-4-phosphatase type I A isoform X25

  30. XM_054341867.1 → XP_054197842.1  inositol polyphosphate-4-phosphatase type I A isoform X27

  31. XM_054341868.1 → XP_054197843.1  inositol polyphosphate-4-phosphatase type I A isoform X28

  32. XM_054341869.1 → XP_054197844.1  inositol polyphosphate-4-phosphatase type I A isoform X29

  33. XM_054341871.1 → XP_054197846.1  inositol polyphosphate-4-phosphatase type I A isoform X31

  34. XM_054341870.1 → XP_054197845.1  inositol polyphosphate-4-phosphatase type I A isoform X30

RNA

  1. XR_008486362.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96PE3.1 GenPept UniProtKB/Swiss-Prot:Q96PE3

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