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Zmynd10 zinc finger, MYND-type containing 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363139, updated on 2-Nov-2024

Summary

Official Symbol
Zmynd10provided by RGD
Official Full Name
zinc finger, MYND-type containing 10provided by RGD
Primary source
RGD:1303250
See related
EnsemblRapid:ENSRNOG00000021602 AllianceGenome:RGD:1303250
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable molecular adaptor activity and protein folding chaperone. Predicted to be involved in cilium assembly and positive regulation of motile cilium assembly. Predicted to act upstream of or within cilium movement; protein folding; and protein localization to cilium. Located in centriolar satellite. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 22. Orthologous to human ZMYND10 (zinc finger MYND-type containing 10). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 229.1), Lung (RPKM 76.3) and 7 other tissues See more
Orthologs
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Genomic context

See Zmynd10 in Genome Data Viewer
Location:
8q32
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (117098790..117103387)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (108220386..108224745)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (116302513..116306871)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene cytochrome b561 family, member D2 Neighboring gene NPR2-like, GATOR1 complex subunit Neighboring gene Ras association domain family member 1 Neighboring gene tumor suppressor 2, mitochondrial calcium regulator

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Clone Names

  • MGC94352

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular adaptor activity ISO
Inferred from Sequence Orthology
more info
 
enables protein folding chaperone ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cilium movement ISO
Inferred from Sequence Orthology
more info
 
involved_in inner dynein arm assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within inner dynein arm assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in inner dynein arm assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in inner dynein arm assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in motile cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within motile cilium assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in motile cilium assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in motile cilium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in outer dynein arm assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within outer dynein arm assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in outer dynein arm assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in outer dynein arm assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of motile cilium assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of motile cilium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within protein folding ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within protein localization to cilium ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in apical plasma membrane ISO
Inferred from Sequence Orthology
more info
 
located_in apical plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in centriolar satellite IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centriolar satellite IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in dynein axonemal particle ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
zinc finger MYND domain-containing protein 10
Names
zinc finger, MYND domain-containing 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004284.1NP_001004284.1  zinc finger MYND domain-containing protein 10

    See identical proteins and their annotated locations for NP_001004284.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079255
    UniProtKB/Swiss-Prot
    Q6AXZ5
    UniProtKB/TrEMBL
    A0A8I6A1M9
    Related
    ENSRNOP00000031055.3, ENSRNOT00000039258.5
    Conserved Domains (1) summary
    pfam01753
    Location:394430
    zf-MYND; MYND finger

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    117098790..117103387
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_010053996.1 RNA Sequence