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Vmac vimentin-type intermediate filament associated coiled-coil protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 363327, updated on 2-Nov-2024

Summary

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Symbol
Vmacprovided by RGD
Full Name
vimentin-type intermediate filament associated coiled-coil proteinprovided by RGD
Primary source
RGD:1303340
See related
EnsemblRapid:ENSRNOG00000065863 AllianceGenome:RGD:1303340
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Located in type III intermediate filament. Orthologous to human VMAC (vimentin type intermediate filament associated coiled-coil protein). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 141.3), Adrenal (RPKM 86.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Vmac in Genome Data Viewer
Location:
9q11
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (1633874..1637538, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (1546747..1550417, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (10338260..10341903)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene lon peptidase 1, mitochondrial Neighboring gene cation channel sperm associated auxiliary subunit delta Neighboring gene RAN binding protein 3 Neighboring gene calcyphosine Neighboring gene NADH:ubiquinone oxidoreductase subunit A11 Neighboring gene fucosyltransferase 4, pseudogene 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Vmac: a novel protein associated with vimentin-type intermediate filament in podocytes of rat kidney. Yamamoto Y, et al. Biochem Biophys Res Commun, 2004 Mar 19. PMID 14985129
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in type III intermediate filament IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in type III intermediate filament IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
vimentin-type intermediate filament-associated coiled-coil protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001720.2 → NP_001001720.1  vimentin-type intermediate filament-associated coiled-coil protein

    See identical proteins and their annotated locations for NP_001001720.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/Swiss-Prot
    Q6QZQ4
    UniProtKB/TrEMBL
    A6KQV3
    Conserved Domains (1) summary
    pfam15272
    Location:35 → 113
    BBP1_C; Spindle pole body component BBP1, C-terminal

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    1633874..1637538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008766765.4 → XP_008764987.3  vimentin-type intermediate filament-associated coiled-coil protein isoform X1

    Related
    ENSRNOP00000096954.2, ENSRNOT00000109435.2
    Conserved Domains (1) summary
    TIGR02168
    Location:40 → 158
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  2. XM_008766766.3 → XP_008764988.1  vimentin-type intermediate filament-associated coiled-coil protein isoform X2

    UniProtKB/TrEMBL
    A0A8I6ARR3
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6QZQ4.1 GenPept UniProtKB/Swiss-Prot:Q6QZQ4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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