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Plin4 perilipin 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 363331, updated on 14-Nov-2024

Summary

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Official Symbol
Plin4provided by RGD
Official Full Name
perilipin 4provided by RGD
Primary source
RGD:1590867
See related
EnsemblRapid:ENSRNOG00000047046 AllianceGenome:RGD:1590867
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in cytosol; lipid droplet; and plasma membrane. Orthologous to human PLIN4 (perilipin 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Heart (RPKM 1545.7), Muscle (RPKM 1495.4) and 4 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Plin4 in Genome Data Viewer
Location:
9q11
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (1016334..1025249, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (929168..938062, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (10963494..10972360)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene chromatin assembly factor 1 subunit A Neighboring gene UBX domain protein 6 Neighboring gene HDGF like 2 Neighboring gene perilipin 5 Neighboring gene leucine-rich alpha-2-glycoprotein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Cloning of cell-specific secreted and surface proteins by subtractive antibody screening. Scherer PE, et al. Nat Biotechnol, 1998 Jun. PMID 9624692
  2. Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine. Moessinger C, et al. J Biol Chem, 2011 Jun 17. PMID 21498505, Free PMC Article
  3. p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes. Dumont AA, et al. Biochim Biophys Acta Mol Cell Res, 2019 Dec. PMID 31505169
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in lipid droplet IEA
Inferred from Electronic Annotation
more info
  
located_in lipid droplet ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
perilipin 4; perilipin-4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001431328.1 → NP_001418257.1  perilipin 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

  2. NM_001431329.1 → NP_001418258.1  perilipin 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

  3. NM_001431330.1 → NP_001418259.1  perilipin 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

  4. NM_001431331.1 → NP_001418260.1  perilipin 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    1016334..1025249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063267952.1 → XP_063124022.1  perilipin-4 isoform X1

    UniProtKB/TrEMBL
    M0R7S5

  2. XM_063267953.1 → XP_063124023.1  perilipin-4 isoform X2

  3. XM_063267954.1 → XP_063124024.1  perilipin-4 isoform X3

    Related
    ENSRNOP00000100884.1, ENSRNOT00000172103.1

  4. XM_006244375.5 → XP_006244437.1  perilipin-4 isoform X3

    Conserved Domains (1) summary
    pfam03036
    Location:1151 → 1411
    Perilipin; Perilipin family

  5. XM_006244374.5 → XP_006244436.1  perilipin-4 isoform X2

    Related
    ENSRNOP00000065507.4, ENSRNOT00000075424.4
    Conserved Domains (1) summary
    pfam03036
    Location:1151 → 1435
    Perilipin; Perilipin family

  6. XM_006244372.5 → XP_006244434.1  perilipin-4 isoform X1

    See identical proteins and their annotated locations for XP_006244434.1

    UniProtKB/TrEMBL
    M0R7S5
    Conserved Domains (1) summary
    pfam03036
    Location:1151 → 1436
    Perilipin; Perilipin family

  7. XM_063267955.1 → XP_063124025.1  perilipin-4 isoform X4

    Related
    ENSRNOP00000107642.1, ENSRNOT00000152784.1

  8. XM_063267956.1 → XP_063124026.1  perilipin-4 isoform X5

  9. XM_063267957.1 → XP_063124027.1  perilipin-4 isoform X6

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Chemical Information
Molecular Biology Databases
Research Materials