Hs3st3a1 heparan sulfate-glucosamine 3-sulfotransferase 3A1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Hs3st3a1provided by RGD
Official Full Name: heparan sulfate-glucosamine 3-sulfotransferase 3A1provided by RGD
Primary source: RGD:1561262
See related: EnsemblRapid:ENSRNOG00000024591 AllianceGenome:RGD:1561262
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Hs3st3a; RGD1561262
Summary: Predicted to enable [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity. Predicted to be involved in branching involved in ureteric bud morphogenesis; glycosaminoglycan biosynthetic process; and heparan sulfate proteoglycan biosynthetic process. Orthologous to human HS3ST3A1 (heparan sulfate-glucosamine 3-sulfotransferase 3A1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Liver (RPKM 39.1), Spleen (RPKM 26.8) and 7 other tissues See more
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Genomic context

Location:: 10q24

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (49593208..49679854)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (49092850..49180676)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (50928309..51014562)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

Hs3st3b1 (e-PCR), detects polymorphism
- UniSTS:532608

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	IBA Inferred from Biological aspect of Ancestor more info
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in branching involved in ureteric bud morphogenesis	ISO Inferred from Sequence Orthology more info
involved_in glycosaminoglycan biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in heparan sulfate proteoglycan biosynthetic process	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: heparan sulfate glucosamine 3-O-sulfotransferase 3A1

Names: heparan sulfate (glucosamine) 3-O-sulfotransferase 3A; heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1

NP_001165538.1

EC 2.8.2.23

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.