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Kctd9 potassium channel tetramerization domain containing 9 [ Rattus norvegicus (Norway rat) ]

Gene ID: 364410, updated on 17-Aug-2024

Summary

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Official Symbol
Kctd9provided by RGD
Official Full Name
potassium channel tetramerization domain containing 9provided by RGD
Primary source
RGD:1312010
See related
EnsemblRapid:ENSRNOG00000012951 AllianceGenome:RGD:1312010
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable cullin family protein binding activity; identical protein binding activity; and protein self-association. Predicted to be involved in intracellular signal transduction and protein homooligomerization. Orthologous to human KCTD9 (potassium channel tetramerization domain containing 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Kidney (RPKM 77.8), Thymus (RPKM 59.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Kctd9 in Genome Data Viewer
Location:
15p12
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (46117211..46145258)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (41942165..41969862)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (44411591..44439645)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene ribosomal protein L36, pseudogene Neighboring gene cell division cycle associated 2 Neighboring gene uncharacterized LOC103693653 Neighboring gene gonadotropin releasing hormone 1 Neighboring gene dedicator of cytokinesis 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Structural Insights into KCTD Protein Assembly and Cullin3 Recognition. Ji AX, et al. J Mol Biol, 2016 Jan 16. PMID 26334369
  2. Next-generation sequencing to generate interactome datasets. Yu H, et al. Nat Methods, 2011 Jun. PMID 21516116, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables cullin family protein binding ISO
Inferred from Sequence Orthology
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
involved_in protein homooligomerization IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
BTB/POZ domain-containing protein KCTD9
Names
potassium channel tetramerisation domain containing 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108871.1 → NP_001102341.1  BTB/POZ domain-containing protein KCTD9

    See identical proteins and their annotated locations for NP_001102341.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474023
    UniProtKB/TrEMBL
    A6K6Q0, D3ZE91
    Related
    ENSRNOP00000017566.3, ENSRNOT00000017566.7
    Conserved Domains (3) summary
    COG1357
    Location:168 → 378
    YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
    cd17073
    Location:2 → 66
    KHA; dimerization domain of potassium ion channel, similar to doublecortin-like domain, found in potassium channel tetramerization domain containing 9 (KCTD9) and similar proteins
    cd18368
    Location:89 → 188
    BTB_POZ_KCTD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 9 (KCTD9)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    46117211..46145258
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063274490.1 → XP_063130560.1  BTB/POZ domain-containing protein KCTD9 isoform X3

    UniProtKB/TrEMBL
    A6K6Q1

  2. XM_063274488.1 → XP_063130558.1  BTB/POZ domain-containing protein KCTD9 isoform X3

    UniProtKB/TrEMBL
    A6K6Q1

  3. XM_006252142.5 → XP_006252204.1  BTB/POZ domain-containing protein KCTD9 isoform X3

    See identical proteins and their annotated locations for XP_006252204.1

    UniProtKB/TrEMBL
    A6K6Q1
    Conserved Domains (2) summary
    COG1357
    Location:54 → 264
    YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
    cl38908
    Location:1 → 74
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

  4. XM_063274491.1 → XP_063130561.1  BTB/POZ domain-containing protein KCTD9 isoform X4

  5. XM_006252138.5 → XP_006252200.1  BTB/POZ domain-containing protein KCTD9 isoform X1

    UniProtKB/TrEMBL
    A0A8I6AP15
    Conserved Domains (3) summary
    COG1357
    Location:223 → 328
    YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
    cd17073
    Location:2 → 66
    KHA; dimerization domain of potassium ion channel, similar to doublecortin-like domain, found in potassium channel tetramerization domain containing 9 (KCTD9) and similar proteins
    cd18368
    Location:89 → 188
    BTB_POZ_KCTD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 9 (KCTD9)

  6. XM_063274487.1 → XP_063130557.1  BTB/POZ domain-containing protein KCTD9 isoform X2

  7. XM_063274489.1 → XP_063130559.1  BTB/POZ domain-containing protein KCTD9 isoform X3

    UniProtKB/TrEMBL
    A6K6Q1

  8. XM_006252141.5 → XP_006252203.1  BTB/POZ domain-containing protein KCTD9 isoform X3

    See identical proteins and their annotated locations for XP_006252203.1

    UniProtKB/TrEMBL
    A6K6Q1
    Related
    ENSRNOP00000082382.1, ENSRNOT00000112078.2
    Conserved Domains (2) summary
    COG1357
    Location:54 → 264
    YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
    cl38908
    Location:1 → 74
    BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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