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Lrrc56 leucine rich repeat containing 56 [ Rattus norvegicus (Norway rat) ]

Gene ID: 365389, updated on 2-Nov-2024

Summary

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Official Symbol
Lrrc56provided by RGD
Official Full Name
leucine rich repeat containing 56provided by RGD
Primary source
RGD:1311654
See related
EnsemblRapid:ENSRNOG00000016697 AllianceGenome:RGD:1311654
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1311654
Summary
Predicted to be involved in cell projection organization. Predicted to be located in cilium. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 39. Orthologous to human LRRC56 (leucine rich repeat containing 56). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Testes (RPKM 125.3), Lung (RPKM 26.6) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Lrrc56 in Genome Data Viewer
Location:
1q41
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (205729402..205744754)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (196299843..196315170)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (214182232..214197184)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ribonuclease/angiogenin inhibitor 1 Neighboring gene U6 spliceosomal RNA Neighboring gene HRas proto-oncogene, GTPase Neighboring gene lamin tail domain containing 2 Neighboring gene Ras association domain family member 7 Neighboring gene uncharacterized LOC102553043 Neighboring gene microRNA 3574 Neighboring gene microRNA 210

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC114503

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cell projection organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cilium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
leucine-rich repeat-containing protein 56

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024902.1 → NP_001020073.1  leucine-rich repeat-containing protein 56

    See identical proteins and their annotated locations for NP_001020073.1

    Status: PROVISIONAL

    Source sequence(s)
    BC097444
    UniProtKB/Swiss-Prot
    Q4V8C9
    UniProtKB/TrEMBL
    A6HXQ9, A6HXR2
    Conserved Domains (2) summary
    sd00033
    Location:95 → 117
    LRR_RI; leucine-rich repeat [structural motif]
    cd21340
    Location:91 → 233
    PPP1R42; protein phosphatase 1 regulatory subunit 42

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    205729402..205744754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230565.5 → XP_006230627.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_006230627.1

    UniProtKB/Swiss-Prot
    Q4V8C9
    UniProtKB/TrEMBL
    A6HXQ9, A6HXR2
    Related
    ENSRNOP00000107955.1, ENSRNOT00000163683.1
    Conserved Domains (2) summary
    sd00033
    Location:95 → 117
    LRR_RI; leucine-rich repeat [structural motif]
    cd21340
    Location:91 → 233
    PPP1R42; protein phosphatase 1 regulatory subunit 42

  2. XM_063269752.1 → XP_063125822.1  leucine-rich repeat-containing protein 56 isoform X4

    UniProtKB/TrEMBL
    A0A0G2K846
    Related
    ENSRNOP00000074468.2, ENSRNOT00000091150.3

  3. XM_063269733.1 → XP_063125803.1  leucine-rich repeat-containing protein 56 isoform X1

    UniProtKB/Swiss-Prot
    Q4V8C9
    UniProtKB/TrEMBL
    A6HXQ9

  4. XM_063269742.1 → XP_063125812.1  leucine-rich repeat-containing protein 56 isoform X2

  5. XM_017589500.3 → XP_017444989.1  leucine-rich repeat-containing protein 56 isoform X4

    UniProtKB/TrEMBL
    A0A0G2K846
    Conserved Domains (4) summary
    cd00116
    Location:54 → 192
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:95 → 117
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:140 → 175
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:117 → 172
    LRR_8; Leucine rich repeat

  6. XM_063269755.1 → XP_063125825.1  leucine-rich repeat-containing protein 56 isoform X4

    UniProtKB/TrEMBL
    A0A0G2K846

  7. XM_006230564.5 → XP_006230626.1  leucine-rich repeat-containing protein 56 isoform X1

    See identical proteins and their annotated locations for XP_006230626.1

    UniProtKB/Swiss-Prot
    Q4V8C9
    UniProtKB/TrEMBL
    A6HXQ9, A6HXR2
    Conserved Domains (2) summary
    sd00033
    Location:95 → 117
    LRR_RI; leucine-rich repeat [structural motif]
    cd21340
    Location:91 → 233
    PPP1R42; protein phosphatase 1 regulatory subunit 42

  8. XM_063269751.1 → XP_063125821.1  leucine-rich repeat-containing protein 56 isoform X4

    UniProtKB/TrEMBL
    A0A0G2K846

  9. XM_063269761.1 → XP_063125831.1  leucine-rich repeat-containing protein 56 isoform X5

  10. XM_017589499.3 → XP_017444988.1  leucine-rich repeat-containing protein 56 isoform X2

    UniProtKB/TrEMBL
    A6HXR2
    Related
    ENSRNOP00000022867.5, ENSRNOT00000022867.8

  11. XM_039085390.2 → XP_038941318.1  leucine-rich repeat-containing protein 56 isoform X1

    UniProtKB/Swiss-Prot
    Q4V8C9
    UniProtKB/TrEMBL
    A6HXQ9, A6HXR2
    Conserved Domains (2) summary
    sd00033
    Location:95 → 117
    LRR_RI; leucine-rich repeat [structural motif]
    cd21340
    Location:91 → 233
    PPP1R42; protein phosphatase 1 regulatory subunit 42

  12. XM_063269753.1 → XP_063125823.1  leucine-rich repeat-containing protein 56 isoform X4

    UniProtKB/TrEMBL
    A0A0G2K846

  13. XM_006230570.5 → XP_006230632.1  leucine-rich repeat-containing protein 56 isoform X3

    See identical proteins and their annotated locations for XP_006230632.1

    UniProtKB/TrEMBL
    A6HXR1, A6HXR2
    Conserved Domains (3) summary
    sd00033
    Location:20 → 42
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12799
    Location:65 → 100
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:42 → 97
    LRR_8; Leucine rich repeat
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4V8C9.1 GenPept UniProtKB/Swiss-Prot:Q4V8C9

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