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Zfp266 zinc finger protein 266 [ Rattus norvegicus (Norway rat) ]

Gene ID: 367034, updated on 17-Aug-2024

Summary

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Official Symbol
Zfp266provided by RGD
Official Full Name
zinc finger protein 266provided by RGD
Primary source
RGD:1308643
See related
EnsemblRapid:ENSRNOG00000034037 AllianceGenome:RGD:1308643
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Zfp426; Znf266; Zfp426l
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF812P (zinc finger protein 812, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Adrenal (RPKM 178.4), Thymus (RPKM 176.8) and 9 other tissues See more
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Genomic context

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See Zfp266 in Genome Data Viewer
Location:
8q13
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (27307015..27338624, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (19030766..19061381, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (21511831..21543275, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 26 Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger protein 426 Neighboring gene ribosomal protein SA, pseudogene 20 Neighboring gene zinc finger protein 846

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 426-like
Names
zinc finger protein 426

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135018.1 → NP_001128490.1  zinc finger protein 426-like

    See identical proteins and their annotated locations for NP_001128490.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    27307015..27338624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039081847.2 → XP_038937775.1  zinc finger protein 426-like isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:328 → 519
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:360 → 380
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:302 → 324
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1 → 28
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

  2. XM_063265865.1 → XP_063121935.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0

  3. XM_039081846.2 → XP_038937774.1  zinc finger protein 426-like isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:328 → 519
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:360 → 380
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:302 → 324
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1 → 28
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

  4. XM_039081845.2 → XP_038937773.1  zinc finger protein 426-like isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:328 → 519
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:360 → 380
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:302 → 324
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1 → 28
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

  5. XM_039081843.2 → XP_038937771.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  6. XM_039081844.2 → XP_038937772.1  zinc finger protein 426-like isoform X2

    Conserved Domains (4) summary
    COG5048
    Location:370 → 561
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:402 → 422
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:344 → 366
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:40 → 80
    KRAB; KRAB box

  7. XM_017595777.3 → XP_017451266.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  8. XM_063265863.1 → XP_063121933.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0

  9. XM_039081848.2 → XP_038937776.1  zinc finger protein 426-like isoform X3

    Conserved Domains (4) summary
    COG5048
    Location:328 → 519
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:360 → 380
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:302 → 324
    zf-C2H2; Zinc finger, C2H2 type
    cl02581
    Location:1 → 28
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box

  10. XM_039081840.2 → XP_038937768.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  11. XM_039081834.2 → XP_038937762.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  12. XM_039081841.2 → XP_038937769.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  13. XM_063265864.1 → XP_063121934.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0

  14. XM_039081835.2 → XP_038937763.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  15. XM_039081836.2 → XP_038937764.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  16. XM_039081842.2 → XP_038937770.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Conserved Domains (4) summary
    smart00349
    Location:41 → 97
    KRAB; krueppel associated box
    COG5048
    Location:397 → 588
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:429 → 449
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:371 → 393
    zf-C2H2; Zinc finger, C2H2 type

  17. XM_063265866.1 → XP_063121936.1  zinc finger protein 426-like isoform X1

    UniProtKB/TrEMBL
    F1MAL0
    Related
    ENSRNOP00000042506.5, ENSRNOT00000042903.7
Nucleotide Protein Strain
Heading Accession and Version

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