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Fam135a family with sequence similarity 135, member A [ Rattus norvegicus (Norway rat) ]

Gene ID: 367235, updated on 10-Oct-2024

Summary

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Official Symbol
Fam135aprovided by RGD
Official Full Name
family with sequence similarity 135, member Aprovided by RGD
Primary source
RGD:1304927
See related
EnsemblRapid:ENSRNOG00000013587 AllianceGenome:RGD:1304927
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1304927
Summary
Predicted to be involved in cellular lipid metabolic process. Orthologous to human FAM135A (family with sequence similarity 135 member A). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Heart (RPKM 130.3), Kidney (RPKM 117.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam135a in Genome Data Viewer
Location:
9q13
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (33916449..33997140, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (26420116..26500803, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (30255057..30335775, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene small ArfGAP 1 Neighboring gene succinate dehydrogenase complex assembly factor 4 Neighboring gene uncharacterized LOC102553447 Neighboring gene collagen type IX alpha 1 chain

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cellular lipid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
protein FAM135A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134597.2 → NP_001128069.2  protein FAM135A isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A6JJB5, D3ZVB3
    Related
    ENSRNOP00000018234.7, ENSRNOT00000018234.9
    Conserved Domains (2) summary
    pfam05057
    Location:1243 → 1438
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  2. NM_001393818.1 → NP_001380747.1  protein FAM135A isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000009
    UniProtKB/TrEMBL
    A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1073 → 1268
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    33916449..33997140 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063267501.1 → XP_063123571.1  protein FAM135A isoform X3

  2. XM_039083961.2 → XP_038939889.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  3. XM_017596557.3 → XP_017452046.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  4. XM_017596560.3 → XP_017452049.1  protein FAM135A isoform X4

    UniProtKB/TrEMBL
    A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1047 → 1242
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein of unknown function (DUF3657)

  5. XM_017596553.3 → XP_017452042.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Related
    ENSRNOP00000080690.1, ENSRNOT00000111990.2
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  6. XM_063267502.1 → XP_063123572.1  protein FAM135A isoform X4

  7. XM_017596554.3 → XP_017452043.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  8. XM_063267499.1 → XP_063123569.1  protein FAM135A isoform X2

    UniProtKB/TrEMBL
    D3ZVB3

  9. XM_063267500.1 → XP_063123570.1  protein FAM135A isoform X3

  10. XM_006244664.4 → XP_006244726.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  11. XM_017596556.3 → XP_017452045.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  12. XM_039083960.2 → XP_038939888.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  13. XM_017596555.3 → XP_017452044.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  14. XM_039083959.2 → XP_038939887.1  protein FAM135A isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZQV8, A6JJB5
    Conserved Domains (2) summary
    pfam05057
    Location:1269 → 1464
    DUF676; Putative serine esterase (DUF676)
    pfam12394
    Location:111 → 171
    DUF3657; Protein FAM135

  15. XM_039083962.2 → XP_038939890.1  protein FAM135A isoform X5

    UniProtKB/TrEMBL
    A6JJB5
    Conserved Domains (1) summary
    pfam05057
    Location:991 → 1186
    DUF676; Putative serine esterase (DUF676)

  16. XM_039083963.2 → XP_038939891.1  protein FAM135A isoform X6

    UniProtKB/TrEMBL
    A6JJB5
    Conserved Domains (1) summary
    pfam05057
    Location:967 → 1162
    DUF676; Putative serine esterase (DUF676)

  17. XM_039083965.2 → XP_038939893.1  protein FAM135A isoform X8

    Conserved Domains (1) summary
    pfam05057
    Location:818 → 1013
    DUF676; Putative serine esterase (DUF676)

  18. XM_039083964.2 → XP_038939892.1  protein FAM135A isoform X7

    Conserved Domains (1) summary
    pfam05057
    Location:849 → 1044
    DUF676; Putative serine esterase (DUF676)

  19. XM_039083966.2 → XP_038939894.1  protein FAM135A isoform X9

    Conserved Domains (1) summary
    pfam05057
    Location:653 → 848
    DUF676; Putative serine esterase (DUF676)
Nucleotide Protein Strain
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