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JUP junction plakoglobin [ Homo sapiens (human) ]

Gene ID: 3728, updated on 3-Nov-2024

Summary

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Official Symbol
JUPprovided by HGNC
Official Full Name
junction plakoglobinprovided by HGNC
Primary source
HGNC:HGNC:6207
See related
Ensembl:ENSG00000173801 MIM:173325; AllianceGenome:HGNC:6207
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PG; DP3; PDGB; PKGB; CTNNG; DPIII
Summary
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
Expression
Broad expression in skin (RPKM 236.9), esophagus (RPKM 189.1) and 16 other tissues See more
Orthologs
mouse all
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Genomic context

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See JUP in Genome Data Viewer
Location:
17q21.2
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (41754609..41786711, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (42611153..42643244, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (39910861..39942963, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 442 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39881045-39881584 Neighboring gene huntingtin associated protein 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:39889784-39890326 Neighboring gene RNA, 7SL, cytoplasmic 399, pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39927459-39927963 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39927964-39928467 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39932003-39932506 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:39942255-39942467 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8499 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:39947785-39948448 Neighboring gene CRISPRi-validated cis-regulatory element chr17.2540 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39956106-39956612 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39956613-39957119 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8500 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12172 Neighboring gene prolyl 3-hydroxylase family member 4 (inactive) Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:39971057-39971558 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:39971559-39972058 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39974907-39975818 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:39975819-39976730 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:39977650-39978248 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:39978249-39978845 Neighboring gene FKBP prolyl isomerase 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Genomic organization and amplification of the human plakoglobin gene (JUP). Whittock NV, et al. Exp Dermatol, 2000 Oct. PMID 11016852
  2. γ-Catenin is an independent prognostic marker in early stage colorectal cancer. Nagel JM, et al. Int J Colorectal Dis, 2010 Nov. PMID 20737155
  3. Homozygous mutations in the 5' region of the JUP gene result in cutaneous disease but normal heart development in children. Cabral RM, et al. J Invest Dermatol, 2010 Jun. PMID 20130592
  4. Reduced plakoglobin immunoreactivity in arrhythmogenic cardiomyopathy: methodological considerations. Noorman M, et al. Cardiovasc Pathol, 2013 Sep-Oct. PMID 23688911
  5. Immunohistochemical analysis of gamma catenin in Wilms' tumors. Basta-Jovanovic G, et al. Fetal Pediatr Pathol, 2008. PMID 18568994

See all (373) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Plakoglobin regulates adipocyte differentiation independently of the Wnt/beta-catenin signaling pathway.
    Title: Plakoglobin regulates adipocyte differentiation independently of the Wnt/β-catenin signaling pathway.
  2. TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP.
    Title: TRIM50 Inhibits Gastric Cancer Progression by Regulating the Ubiquitination and Nuclear Translocation of JUP.
  3. Plakoglobin and High-Mobility Group Box 1 Mediate Intestinal Epithelial Cell Apoptosis Induced by Clostridioides difficile TcdB.
    Title: Plakoglobin and High-Mobility Group Box 1 Mediate Intestinal Epithelial Cell Apoptosis Induced by Clostridioides difficile TcdB.
  4. ICAT promotes colorectal cancer metastasis via binding to JUP and activating the NF-kappaB signaling pathway.
    Title: ICAT promotes colorectal cancer metastasis via binding to JUP and activating the NF-κB signaling pathway.
  5. Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets.
    Title: Opposing prognostic relevance of junction plakoglobin in distinct prostate cancer patient subsets.
  6. KRT13 promotes stemness and drives metastasis in breast cancer through a plakoglobin/c-Myc signaling pathway.
    Title: KRT13 promotes stemness and drives metastasis in breast cancer through a plakoglobin/c-Myc signaling pathway.
  7. Ral GEF with the PH Domain and SH3 Binding Motif 1 Regulated by Splicing Factor Junction Plakoglobin and Pyrimidine Metabolism Are Prognostic in Uterine Carcinosarcoma.
    Title: Ral GEF with the PH Domain and SH3 Binding Motif 1 Regulated by Splicing Factor Junction Plakoglobin and Pyrimidine Metabolism Are Prognostic in Uterine Carcinosarcoma.
  8. JUP/plakoglobin is regulated by salt-inducible kinase 2, and is required for insulin-induced signalling and glucose uptake in adipocytes.
    Title: JUP/plakoglobin is regulated by salt-inducible kinase 2, and is required for insulin-induced signalling and glucose uptake in adipocytes.
  9. Junction plakoglobin regulates and destabilizes HIF2alpha to inhibit tumorigenesis of renal cell carcinoma.
    Title: Junction plakoglobin regulates and destabilizes HIF2α to inhibit tumorigenesis of renal cell carcinoma.
  10. Arrhythmogenic right ventricular cardiomyopathy in patients with biallelic JUP-associated skin fragility.
    Title: Arrhythmogenic right ventricular cardiomyopathy in patients with biallelic JUP-associated skin fragility.
Submit: New GeneRIF Correction See all GeneRIFs (94)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables alpha-catenin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alpha-catenin binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cadherin binding HDA PubMed 
enables cadherin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cadherin binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cell adhesion molecule binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication IC
Inferred by Curator
more info
 PubMed 
enables cytoskeletal protein-membrane anchor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nuclear receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein phosphatase binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein phosphatase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural molecule activity NAS
Non-traceable Author Statement
more info
 PubMed 
enables transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transcription coactivator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in bundle of His cell-Purkinje myocyte adhesion involved in cell communication IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell migration IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell-cell adhesion IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cell-cell adhesion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to indole-3-methanol IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in desmosome assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in desmosome assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in detection of mechanical stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in endothelial cell-cell adhesion ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of blood vessel endothelial cell migration IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of angiogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of canonical Wnt signaling pathway IC
Inferred by Curator
more info
 PubMed 
involved_in positive regulation of cell-matrix adhesion IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of protein import into nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell population proliferation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of heart rate by cardiac conduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of ventricular cardiac muscle cell action potential IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in skin development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
  
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in adherens junction IDA
Inferred from Direct Assay
more info
 PubMed 
part_of catenin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of catenin complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell-cell junction IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cornified envelope TAS
Traceable Author Statement
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in cytoplasmic side of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in desmosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular exosome HDA PubMed 
located_in extracellular region TAS
Traceable Author Statement
more info
  
located_in ficolin-1-rich granule lumen TAS
Traceable Author Statement
more info
  
located_in focal adhesion HDA PubMed 
part_of gamma-catenin-TCF7L2 complex IDA
Inferred from Direct Assay
more info
 PubMed 
NOT located_in hemidesmosome ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in intercalated disc IDA
Inferred from Direct Assay
more info
 PubMed 
located_in intermediate filament IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
  
part_of protein-DNA complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in specific granule lumen TAS
Traceable Author Statement
more info
  
located_in zonula adherens ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
junction plakoglobin
Names
catenin (cadherin-associated protein), gamma 80kDa
desmoplakin III
desmoplakin-3
desmosomal protein 3

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_009090.2 RefSeqGene

    Range
    5001..37106
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_401

mRNA and Protein(s)

  1. NM_001352773.2 → NP_001339702.1  junction plakoglobin

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) represents the longest transcript. Variants 1-7 encode the same protein.
    Source sequence(s)
    AC109319
    Consensus CDS
    CCDS11407.1
    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  2. NM_001352774.2 → NP_001339703.1  junction plakoglobin

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks alternate segments in the 5' and 3' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein.
    Source sequence(s)
    AC109319
    Consensus CDS
    CCDS11407.1
    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  3. NM_001352775.2 → NP_001339704.1  junction plakoglobin

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) lacks alternate segments in the 5' and 3' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein.
    Source sequence(s)
    AC109319
    Consensus CDS
    CCDS11407.1
    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  4. NM_001352776.2 → NP_001339705.1  junction plakoglobin

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) has multiple differences in the 5' and 3' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein.
    Source sequence(s)
    AC109319
    Consensus CDS
    CCDS11407.1
    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  5. NM_001352777.2 → NP_001339706.1  junction plakoglobin

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) has a novel exon in the 5' UTR and lacks an alternate segment in the 3' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein.
    Source sequence(s)
    AC109319
    Consensus CDS
    CCDS11407.1
    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  6. NM_002230.4 → NP_002221.1  junction plakoglobin

    See identical proteins and their annotated locations for NP_002221.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) lacks an alternate segment in the 5' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein.
    Source sequence(s)
    AC109319
    Consensus CDS
    CCDS11407.1
    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Related
    ENSP00000377508.3, ENST00000393931.8
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  7. NM_021991.4 → NP_068831.1  junction plakoglobin

    See identical proteins and their annotated locations for NP_068831.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an alternate segment in the 3' UTR, compared to transcript variant 3. Variants 1-7 encode the same protein.
    Source sequence(s)
    AC109319
    Consensus CDS
    CCDS11407.1
    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Related
    ENSP00000311113.5, ENST00000310706.9
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    41754609..41786711 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047435939.1 → XP_047291895.1  junction plakoglobin isoform X2

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487

  2. XM_047435934.1 → XP_047291890.1  junction plakoglobin isoform X1

  3. XM_006721874.4 → XP_006721937.1  junction plakoglobin isoform X2

    See identical proteins and their annotated locations for XP_006721937.1

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  4. XM_047435935.1 → XP_047291891.1  junction plakoglobin isoform X1

  5. XM_006721875.2 → XP_006721938.1  junction plakoglobin isoform X2

    See identical proteins and their annotated locations for XP_006721938.1

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  6. XM_047435942.1 → XP_047291898.1  junction plakoglobin isoform X2

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487

  7. XM_011524758.2 → XP_011523060.1  junction plakoglobin isoform X2

    See identical proteins and their annotated locations for XP_011523060.1

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  8. XM_047435937.1 → XP_047291893.1  junction plakoglobin isoform X1

  9. XM_047435941.1 → XP_047291897.1  junction plakoglobin isoform X2

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487

  10. XM_017024590.2 → XP_016880079.1  junction plakoglobin isoform X2

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Conserved Domains (4) summary
    smart00185
    Location:341 → 381
    ARM; Armadillo/beta-catenin-like repeats
    PLN03200
    Location:328 → 658
    PLN03200; cellulose synthase-interactive protein; Provisional
    sd00043
    Location:393 → 418
    ARM; armadillo repeat [structural motif]
    pfam00514
    Location:221 → 253
    Arm; Armadillo/beta-catenin-like repeat

  11. XM_047435940.1 → XP_047291896.1  junction plakoglobin isoform X2

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487

  12. XM_047435938.1 → XP_047291894.1  junction plakoglobin isoform X2

    UniProtKB/Swiss-Prot
    P14923, Q15093, Q15151, Q7L3S5, Q86W21, Q9BWC4, Q9HCX9
    UniProtKB/TrEMBL
    A0A0S2Z487
    Related
    ENSP00000377507.1, ENST00000393930.5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    42611153..42643244 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054315984.1 → XP_054171959.1  junction plakoglobin isoform X1

  2. XM_054315986.1 → XP_054171961.1  junction plakoglobin isoform X2

  3. XM_054315989.1 → XP_054171964.1  junction plakoglobin isoform X2

  4. XM_054315988.1 → XP_054171963.1  junction plakoglobin isoform X2

  5. XM_054315983.1 → XP_054171958.1  junction plakoglobin isoform X1

  6. XM_054315992.1 → XP_054171967.1  junction plakoglobin isoform X2

  7. XM_054315987.1 → XP_054171962.1  junction plakoglobin isoform X2

  8. XM_054315985.1 → XP_054171960.1  junction plakoglobin isoform X1

  9. XM_054315993.1 → XP_054171968.1  junction plakoglobin isoform X2

  10. XM_054315991.1 → XP_054171966.1  junction plakoglobin isoform X2

  11. XM_054315990.1 → XP_054171965.1  junction plakoglobin isoform X2

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P14923.3 GenPept UniProtKB/Swiss-Prot:P14923

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