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nw narrow [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772015, updated on 2-Nov-2024

Summary

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Official Symbol
nwprovided by FlyBase
Official Full Name
narrowprovided by FlyBase
Primary source
FLYBASE:FBgn0283508
Locus tag
Dmel_CG43164
See related
AllianceGenome:FB:FBgn0283508
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:fe2D7; anon2D7; Bla; CG18431; CG33006; CG43164; CG4844; CG4844a; CG4844b; Dmel\CG43164; lance
Old locus tag
Dmel_CG18431; Dmel_CG4844
Summary
Predicted to enable carbohydrate binding activity and pattern recognition receptor activity. Involved in regulation of imaginal disc-derived wing size. Located in extracellular space. Is expressed in several structures, including clypeo-labral primordium; embryonic head epidermis; epidermis; gut section; and sense organ. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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Location:
54B18-54C1; 2-82 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17502354..17508645)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13389859..13396150)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ecto-5'-nucleotidase 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cathepsin K2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crossover Modifiers in the Third Chromosome of DROSOPHILA MELANOGASTER. Payne F. Genetics, 1924 Jul. PMID 17246043, Free PMC Article
  2. A narrow gene encoding an extracellular matrix is involved in the formation of the footpad hairs in Drosophila melanogaster. Tanaka K, et al. MicroPubl Biol, 2023. PMID 37090156, Free PMC Article
  3. Enhanced flight performance by genetic manipulation of wing shape in Drosophila. Ray RP, et al. Nat Commun, 2016 Mar 1. PMID 26926954, Free PMC Article
  4. The mus206 gene of Drosophila melanogaster is required in the excision repair of alkylation-induced DNA lesions. Huang W, et al. Mutat Res, 1997 Aug. PMID 9298117
  5. Oogenesis in adult Drosophila melanogaster. IV. Hereditary ovarian tumors. KING RC, et al. Growth, 1957 Dec. PMID 13512753

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables carbohydrate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables pattern recognition receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of imaginal disc-derived wing size IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
narrow
Names
CG43164-PA
CG43164-PB
CG43164-PC
CG43164-PD
CG43164-PE
anon-fast-evolving-2D7
blade
nw-PA
nw-PB
nw-PC
nw-PD
nw-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    17502354..17508645
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001032264.4 → NP_001027435.2  narrow, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027435.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    C3KGN2
    Conserved Domains (1) summary
    cd00037
    Location:31 → 176
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

  2. NM_001032266.4 → NP_001027437.1  narrow, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027437.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAU2
    Conserved Domains (1) summary
    cd00037
    Location:42 → 176
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

  3. NM_001202034.3 → NP_001188963.1  narrow, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001188963.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4JCT4
    Conserved Domains (1) summary
    cd00037
    Location:42 → 175
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

  4. NM_001032265.4 → NP_001027436.2  narrow, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027436.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAU3
    Conserved Domains (1) summary
    cd00037
    Location:31 → 175
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

  5. NM_001259468.2 → NP_001246397.1  narrow, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001246397.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1ZAU2
    Conserved Domains (1) summary
    cd00037
    Location:42 → 176
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4JCT4 A0A0B4JCT4
A1ZAU2 A1ZAU2
A1ZAU3 A1ZAU3
C3KGN2 C3KGN2
O16054 O16054
Q7K140 Q7K140

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