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Adhr Adh-related [ Drosophila melanogaster (fruit fly) ]

Gene ID: 3772432, updated on 2-Nov-2024

Summary

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Official Symbol
Adhrprovided by FlyBase
Official Full Name
Adh-relatedprovided by FlyBase
Primary source
FLYBASE:FBgn0000056
Locus tag
Dmel_CG3484
See related
AllianceGenome:FB:FBgn0000056
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
3'ORF; Adh-dup; ADHR; Adh[r]; ADH[r]; BG:DS01486.9; CG32954; CG3484; Dmel\CG3484
Summary
Predicted to be active in cytoplasm. Is expressed in several structures, including embryonic/larval garland cell; embryonic/larval midgut; ganglia; primordial germ cell; and visceral mesoderm derivative. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See Adhr in Genome Data Viewer
Location:
35B3-35B3; 2-50 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (14615552..14618902)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (14615552..14618902)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene transfer RNA:Proline-AGG 1-4 Neighboring gene long non-coding RNA:CR43411 Neighboring gene outspread Neighboring gene Alcohol dehydrogenase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deletions at intervening sequence splice sites in the alcohol dehydrogenase gene of Drosophila. Benyajati C, et al. Nucleic Acids Res, 1982 Nov 25. PMID 6296769, Free PMC Article
  2. The Drosophila alcohol dehydrogenase gene may have evolved independently of the functionally homologous medfly, olive fly, and flesh fly genes. Brogna S, et al. Mol Biol Evol, 2001 Mar. PMID 11230533
  3. Structural analysis of an electrophoretically cryptic alcohol dehydrogenase variant from an Australian population of Drosophila melanogaster. Chambers GK, et al. Proc Natl Acad Sci U S A, 1981 May. PMID 6789328, Free PMC Article
  4. In vitro suppression of a nonsense mutant of Drosophila melanogaster. Kubli E, et al. Nucleic Acids Res, 1982 Nov 25. PMID 6818527, Free PMC Article
  5. Alcohol dehydrogenase gene of Drosophila melanogaster: relationship of intervening sequences to functional domains in the protein. Benyajati C, et al. Proc Natl Acad Sci U S A, 1981 May. PMID 6789320, Free PMC Article

See all (102) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The translation mechanism of the dicistronic Adh-Adhr mRNA of Drosophila melanogaster, was investigated.
    Title: The intergenic spacer of the Drosophila Adh-Adhr dicistronic mRNA stimulates internal translation initiation.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
NOT enables NAD binding TAS
Traceable Author Statement
more info
 PubMed 
NOT enables alcohol dehydrogenase (NAD+) activity TAS
Traceable Author Statement
more info
 PubMed 
NOT enables oxidoreductase activity TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Adh-related
Names
Adh related
Adhr-PA
Adhr-PB
Adhr-PC
CG3484-PA
CG3484-PB
CG3484-PC
alcohol dehydrogenase related
alcohol dehydrogenase-related

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    14615552..14618902
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_058147.4 → NP_477495.1  Adh-related, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477495.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0Q4, P91615, Q24230, Q6LAE8, Q9NKB9, Q9VJS2
    UniProtKB/TrEMBL
    X2JAH0
    Conserved Domains (2) summary
    cd05323
    Location:7 → 248
    ADH_SDR_c_like; insect type alcohol dehydrogenase (ADH)-like, classical (c) SDRs
    pfam00106
    Location:7 → 195
    adh_short; short chain dehydrogenase

  2. NM_001032101.2 → NP_001027272.1  Adh-related, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001027272.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0Q4, P91615, Q24230, Q6LAE8, Q9NKB9, Q9VJS2
    UniProtKB/TrEMBL
    X2JAH0
    Conserved Domains (2) summary
    cd05323
    Location:7 → 248
    ADH_SDR_c_like; insect type alcohol dehydrogenase (ADH)-like, classical (c) SDRs
    pfam00106
    Location:7 → 195
    adh_short; short chain dehydrogenase

  3. NM_001299009.1 → NP_001285938.1  Adh-related, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285938.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A4V0Q4, P91615, Q24230, Q6LAE8, Q9NKB9, Q9VJS2
    UniProtKB/TrEMBL
    X2JAH0
    Conserved Domains (2) summary
    cd05323
    Location:7 → 248
    ADH_SDR_c_like; insect type alcohol dehydrogenase (ADH)-like, classical (c) SDRs
    pfam00106
    Location:7 → 195
    adh_short; short chain dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P91615.1 P91615
X2JAH0 X2JAH0

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