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drd2b - dopamine receptor D2b

Predicted to enable G protein-coupled receptor activity and dopamine neurotransmitter receptor activity, coupled via Gi/Go. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; negative regulation of glutamatergic synaptic transmission; and regulation of dopamine secretion. Predicted to act upstream of or within G protein-coupled dopamine receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in glutamatergic synapse and presynaptic membrane. Is expressed in nervous system and notochord. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; drug dependence (multiple); end stage renal disease; nicotine dependence; and type 2 diabetes mellitus. Orthologous to human DRD2 (dopamine receptor D2). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to drd2b

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Species Gene Architecture aa