U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

WIP1 Wip1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 3799971, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
WIP1
Official Full Name
Wip1p
Primary source
SGD:S000113553
Locus tag
YDR374W-A
See related
AllianceGenome:SGD:S000113553; FungiDB:YDR374W-A; VEuPathDB:YDR374W-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables centromeric DNA binding activity. Involved in chromosome segregation. Located in kinetochore. [provided by Alliance of Genome Resources, Apr 2022]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See WIP1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1224757..1225026)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene frequenin Neighboring gene mRNA-binding phosphate metabolism regulator Neighboring gene bifunctional AAA family ATPase chaperone/translocase BCS1 Neighboring gene NADPH-adrenodoxin reductase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex. Zhang Z, et al. Nucleic Acids Res, 2020 Nov 4. PMID 32976599, Free PMC Article
  2. A dCas9-Based System Identifies a Central Role for Ctf19 in Kinetochore-Derived Suppression of Meiotic Recombination. Kuhl LM, et al. Genetics, 2020 Oct. PMID 32843356, Free PMC Article
  3. The kinetochore prevents centromere-proximal crossover recombination during meiosis. Vincenten N, et al. Elife, 2015 Dec 14. PMID 26653857, Free PMC Article
  4. The Structural Basis for Kinetochore Stabilization by Cnn1/CENP-T. Hinshaw SM, et al. Curr Biol, 2020 Sep 7. PMID 32679099
  5. Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Cliften P, et al. Science, 2003 Jul 4. PMID 12775844

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables centromeric DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromosome segregation IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IDA
Inferred from Direct Assay
more info
 PubMed 
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Wip1p
NP_001032576.1
  • Kinetochore localized hypothetical protein; interacts with Cnn1p (CENP-T); orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-W and fission yeast new1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1224757..1225026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184680.1 → NP_001032576.1  TPA: Wip1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_001032576.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VT06, Q2V2P8
    UniProtKB/TrEMBL
    A6ZYX3, B3LFS8, C7GMG2, C8Z5T7, G2WBB1, N1P727
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2V2P8.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools