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Atxn7l1 ataxin 7-like 1 [ Mus musculus (house mouse) ]

Gene ID: 380753, updated on 2-Nov-2024

Summary

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Official Symbol
Atxn7l1provided by MGI
Official Full Name
ataxin 7-like 1provided by MGI
Primary source
MGI:MGI:3584458
See related
Ensembl:ENSMUSG00000020564 AllianceGenome:MGI:3584458
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atxn7l4; 2810423G08Rik
Summary
Orthologous to human ATXN7L1 (ataxin 7 like 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis adult (RPKM 6.9), thymus adult (RPKM 6.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Atxn7l1 in Genome Data Viewer
Location:
12 A3; 12 14.03 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (33196967..33426407)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (33146968..33376408)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40874 Neighboring gene predicted gene, 24922 Neighboring gene cadherin-related family member 3 Neighboring gene RIKEN cDNA F730043M19 gene Neighboring gene STARR-seq mESC enhancer starr_31887 Neighboring gene STARR-positive B cell enhancer ABC_E11509 Neighboring gene predicted gene, 38649 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:33987074-33987296 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:34000210-34000400 Neighboring gene ataxin 7-like 1, opposite strand 2 Neighboring gene STARR-seq mESC enhancer starr_31895 Neighboring gene EF-hand calcium binding domain 10 Neighboring gene STARR-seq mESC enhancer starr_31896 Neighboring gene STARR-positive B cell enhancer ABC_E2381 Neighboring gene RNA polymerase I subunit F

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Clone Names

  • MGC28883

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
ataxin-7-like protein 1
Names
ataxin 7-like 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033436.3 → NP_001028608.3  ataxin-7-like protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001028608.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1), as well as variant 7, encodes isoform 1.
    Source sequence(s)
    AC160112
    Consensus CDS
    CCDS25875.1
    UniProtKB/TrEMBL
    B2RW07, Q3U1F1
    Related
    ENSMUSP00000088085.5, ENSMUST00000090597.11
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  2. NM_001374022.1 → NP_001360951.1  ataxin-7-like protein 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes the longest isoform (3).
    Source sequence(s)
    AC132312, AC132354, AC160112
    UniProtKB/TrEMBL
    F7C0E4
    Conserved Domains (1) summary
    pfam08313
    Location:274 → 340
    SCA7; zinc-binding domain

  3. NM_001374023.1 → NP_001360952.1  ataxin-7-like protein 1 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC132312, AC132354, AC160112
    UniProtKB/TrEMBL
    F6X2K7
    Conserved Domains (1) summary
    pfam08313
    Location:274 → 340
    SCA7; zinc-binding domain

  4. NM_001374024.1 → NP_001360953.1  ataxin-7-like protein 1 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AC160112
    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  5. NM_001374025.1 → NP_001360954.1  ataxin-7-like protein 1 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC160112
    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:165 → 231
    SCA7; zinc-binding domain

  6. NM_001374026.1 → NP_001360955.1  ataxin-7-like protein 1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7), as well as variant 1, encodes isoform 1.
    Source sequence(s)
    AC160112
    Consensus CDS
    CCDS25875.1
    UniProtKB/TrEMBL
    B2RW07, Q3U1F1
    Related
    ENSMUSP00000122982.2, ENSMUST00000154742.2
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  7. NM_028139.5 → NP_082415.2  ataxin-7-like protein 1 isoform 2

    See identical proteins and their annotated locations for NP_082415.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) shares no exons with variant 1. The encoded protein (isoform 2) thus shares no sequence with isoform 1. This variant is transcribed from the 5' end of the locus.
    Source sequence(s)
    AC132312, AC132354, AK013145
    Consensus CDS
    CCDS25874.2
    UniProtKB/Swiss-Prot
    Q8VD60, Q9CZ05
    Related
    ENSMUSP00000106448.3, ENSMUST00000110824.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    33196967..33426407
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515129.5 → XP_006515192.1  ataxin-7-like protein 1 isoform X6

    UniProtKB/TrEMBL
    F6X2K7
    Conserved Domains (1) summary
    pfam08313
    Location:274 → 340
    SCA7; zinc-binding domain

  2. XM_006515130.5 → XP_006515193.1  ataxin-7-like protein 1 isoform X7

    UniProtKB/TrEMBL
    F6X2K7
    Related
    ENSMUSP00000118777.3, ENSMUST00000125192.9
    Conserved Domains (1) summary
    pfam08313
    Location:274 → 340
    SCA7; zinc-binding domain

  3. XM_006515124.5 → XP_006515187.1  ataxin-7-like protein 1 isoform X1

    UniProtKB/TrEMBL
    F7C0E4
    Related
    ENSMUSP00000122156.3, ENSMUST00000146040.9
    Conserved Domains (1) summary
    pfam08313
    Location:274 → 340
    SCA7; zinc-binding domain

  4. XM_036157509.1 → XP_036013402.1  ataxin-7-like protein 1 isoform X9

    UniProtKB/TrEMBL
    F6X2K7
    Conserved Domains (1) summary
    pfam08313
    Location:257 → 317
    SCA7; zinc-binding domain

  5. XM_006515125.5 → XP_006515188.1  ataxin-7-like protein 1 isoform X2

    UniProtKB/TrEMBL
    F7C0E4
    Conserved Domains (1) summary
    pfam08313
    Location:274 → 340
    SCA7; zinc-binding domain

  6. XM_006515128.5 → XP_006515191.1  ataxin-7-like protein 1 isoform X4

    UniProtKB/TrEMBL
    F6X2K7
    Conserved Domains (1) summary
    pfam08313
    Location:274 → 340
    SCA7; zinc-binding domain

  7. XM_006515126.5 → XP_006515189.1  ataxin-7-like protein 1 isoform X3

    UniProtKB/TrEMBL
    F7C0E4
    Conserved Domains (1) summary
    pfam08313
    Location:251 → 317
    SCA7; zinc-binding domain

  8. XM_006515134.5 → XP_006515197.1  ataxin-7-like protein 1 isoform X8

    See identical proteins and their annotated locations for XP_006515197.1

    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  9. XM_006515133.2 → XP_006515196.1  ataxin-7-like protein 1 isoform X8

    See identical proteins and their annotated locations for XP_006515196.1

    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  10. XM_036157510.1 → XP_036013403.1  ataxin-7-like protein 1 isoform X15

    UniProtKB/TrEMBL
    Q3TYJ2

  11. XM_006515132.5 → XP_006515195.1  ataxin-7-like protein 1 isoform X8

    See identical proteins and their annotated locations for XP_006515195.1

    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  12. XM_030246802.2 → XP_030102662.1  ataxin-7-like protein 1 isoform X12

    UniProtKB/TrEMBL
    B2RW07, Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  13. XM_017315123.3 → XP_017170612.1  ataxin-7-like protein 1 isoform X5

    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:165 → 231
    SCA7; zinc-binding domain

  14. XM_011243881.4 → XP_011242183.1  ataxin-7-like protein 1 isoform X13

    See identical proteins and their annotated locations for XP_011242183.1

    UniProtKB/TrEMBL
    D3Z7I2
    Conserved Domains (1) summary
    pfam08313
    Location:150 → 216
    SCA7; zinc-binding domain

  15. XM_030246803.1 → XP_030102663.1  ataxin-7-like protein 1 isoform X14

    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:58 → 124
    SCA7; zinc-binding domain

  16. XM_006515136.3 → XP_006515199.1  ataxin-7-like protein 1 isoform X11

    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:58 → 124
    SCA7; zinc-binding domain

  17. XM_017315124.3 → XP_017170613.1  ataxin-7-like protein 1 isoform X10

    UniProtKB/TrEMBL
    Q3U1F1
    Conserved Domains (1) summary
    pfam08313
    Location:91 → 157
    SCA7; zinc-binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CZ05.2 GenPept UniProtKB/Swiss-Prot:Q9CZ05

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