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Lbhd2 LBH domain containing 2 [ Mus musculus (house mouse) ]

Gene ID: 380787, updated on 2-Nov-2024

Summary

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Official Symbol
Lbhd2provided by MGI
Official Full Name
LBH domain containing 2provided by MGI
Primary source
MGI:MGI:2685744
See related
Ensembl:ENSMUSG00000087075 AllianceGenome:MGI:2685744
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Lbh2; Gm898; A230065H16Rik
Summary
Is expressed in forebrain. Orthologous to human LBHD2 (LBH domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in frontal lobe adult (RPKM 3.4), limb E14.5 (RPKM 2.7) and 10 other tissues See more
Orthologs
human all
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Genomic context

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See Lbhd2 in Genome Data Viewer
Location:
12 F1; 12 60.98 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (111368485..111378526)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (111402049..111412092)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51960 Neighboring gene RIKEN cDNA A230087F16 gene Neighboring gene amnionless Neighboring gene CDC42 binding protein kinase beta Neighboring gene exocyst complex component 3-like 4 Neighboring gene tumor necrosis factor, alpha-induced protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Value-related learning in the olfactory bulb occurs through pathway-dependent perisomatic inhibition of mitral cells. Lindeman S, et al. PLoS Biol, 2024 Mar. PMID 38427708, Free PMC Article
  2. Use of laser-capture microdissection for the identification of marker genes for the ventromedial hypothalamic nucleus. Segal JP, et al. J Neurosci, 2005 Apr 20. PMID 15843621, Free PMC Article
  3. Generation and Characterization of a Cell Type-Specific, Inducible Cre-Driver Line to Study Olfactory Processing. Koldaeva A, et al. J Neurosci, 2021 Jul 28. PMID 34099512, Free PMC Article
  4. A genomic atlas of mouse hypothalamic development. Shimogori T, et al. Nat Neurosci, 2010 Jun. PMID 20436479, Free PMC Article
  5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
LBH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101503.2 → NP_001094973.1  LBH domain-containing protein 2

    See identical proteins and their annotated locations for NP_001094973.1

    Status: VALIDATED

    Source sequence(s)
    AK038816, AW046934
    Consensus CDS
    CCDS49180.1
    UniProtKB/TrEMBL
    G3UW55
    Related
    ENSMUSP00000128648.2, ENSMUST00000150384.3
    Conserved Domains (1) summary
    pfam15317
    Location:26 → 61
    Lbh; Cardiac transcription factor regulator, Developmental protein

  2. NM_001358956.1 → NP_001345885.1  LBH domain-containing protein 2

    Status: VALIDATED

    Source sequence(s)
    AK038816, AW046934, BE649301
    Consensus CDS
    CCDS49180.1
    UniProtKB/TrEMBL
    G3UW55
    Conserved Domains (1) summary
    pfam15317
    Location:26 → 61
    Lbh; Cardiac transcription factor regulator, Developmental protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    111368485..111378526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516048.3 → XP_006516111.1  LBH domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006516111.1

    UniProtKB/TrEMBL
    G3UW55
    Conserved Domains (1) summary
    pfam15317
    Location:26 → 61
    Lbh; Cardiac transcription factor regulator, Developmental protein

  2. XM_006516047.5 → XP_006516110.1  LBH domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_006516110.1

    UniProtKB/TrEMBL
    G3UW55
    Conserved Domains (1) summary
    pfam15317
    Location:26 → 61
    Lbh; Cardiac transcription factor regulator, Developmental protein
Nucleotide Protein Strain
Heading Accession and Version

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