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KIR3DL2 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 [ Homo sapiens (human) ]

Gene ID: 3812, updated on 28-Oct-2024

Summary

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Official Symbol
KIR3DL2provided by HGNC
Official Full Name
killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2provided by HGNC
Primary source
HGNC:HGNC:6339
See related
Ensembl:ENSG00000240403 MIM:604947; AllianceGenome:HGNC:6339
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
3DL2; p140; NKAT4; CD158K; NKAT-4; NKAT4B; KIR-3DL2
Summary
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011]
Expression
Low expression observed in reference dataset See more
Orthologs
all
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Genomic context

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See KIR3DL2 in Genome Data Viewer
Location:
19q13.42
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (54850443..54867207)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (57944772..57961522)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (55361898..55378662)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 Neighboring gene killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 (gene/pseudogene) Neighboring gene RNA, U6 small nuclear 222, pseudogene Neighboring gene MPRA-validated peak3560 silencer Neighboring gene Sharpr-MPRA regulatory region 15416 Neighboring gene Fc alpha receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. [Allelic polymorphism analysis of killer cell immunoglobulin-like receptor gene 3DL2 in Zhejiang Han population]. Jiang K, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2006 Jun. PMID 16767680
  2. Lipopolysaccharide stimulates the proliferation of human CD56+CD3- NK cells: a regulatory role of monocytes and IL-10. Goodier MR, et al. J Immunol, 2000 Jul 1. PMID 10861046
  3. KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis. Wong-Baeza I, et al. J Immunol, 2013 Apr 1. PMID 23440420, Free PMC Article
  4. KIR3DL2/CpG ODN interaction mediates Sézary syndrome malignant T cell apoptosis. Ghazi B, et al. J Invest Dermatol, 2015 Jan. PMID 25007046
  5. Genetic polymorphisms of killer cell immunoglobulin-like receptor 3DL2 in preeclampsia. Wang XL, et al. J Perinat Med, 2011 May. PMID 21406041

See all (118) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Activating KIR/HLA-I combinations as a risk factor of adult B-ALL.
    Title: Activating KIR/HLA-I combinations as a risk factor of adult B-ALL.
  2. CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome.
    Title: CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome.
  3. [Study of the distribution of KIR3DL2 alleles among ethnic Han Chinese from Zhejiang].
    Title: [Study of the distribution of KIR3DL2 alleles among ethnic Han Chinese from Zhejiang].
  4. Study found that KIR3DL2 is expressed in tissue tumor-infiltrating cells in the majority of patients with adult T-cell lymphoma/leukemia. Disease-specific survival of patients with KIR3DL2 expression > 50% was statistically significantly decreased compared with patients with KIR3DL2 expression < 5% or KIR3DL2 expression between 5% and 50%.
    Title: KIR3DL2 expression in patients with adult T-cell lymphoma/leukaemia.
  5. We show that KIR3DL2 expression is the most sensitive diagnostic criterion of Sezary syndrome when compared with all other available biological criteria. KIR3DL2 therefore represents a valuable tool for routine use as a clinical parameter at diagnosis, for prognosis and during patient follow-up
    Title: Usefulness of KIR3DL2 to Diagnose, Follow-Up, and Manage the Treatment of Patients with Sézary Syndrome.
  6. results identified significant KIR3DL2 expression in all cutaneous T-cell lymphomas subtypes
    Title: KIR3DL2 expression in cutaneous T-cell lymphomas: expanding the spectrum for KIR3DL2 targeting.
  7. Overexpression of a single MHCI molecule, HLA-F, protects human MNs from ALS astrocyte-mediated toxicity, whereas knockdown of its receptor, the killer cell immunoglobulin-like receptor KIR3DL2, on human astrocytes results in enhanced motor neurons death
    Title: Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.
  8. KIR-3DL2 binding to HLA-B27 licenses Th17 cell differentiation in spondyloarthritis.
    Title: Activation-Induced Killer Cell Immunoglobulin-like Receptor 3DL2 Binding to HLA-B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis.
  9. In early axial spondyloarthritis and ankylosing spondylitis Dutch patients, no copy number changes were found for KIR3DL2.
    Title: KIR3DL1 and KIR3DL2 gene copy number variation in axial spondyloarthritis.
  10. we show that the allele KIR3DL2*001 and the single nucleotide polymorphism 1190T (rs3745902) are associated with differential susceptibility to pemphigus
    Title: Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo.
Submit: New GeneRIF Correction See all GeneRIFs (40)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC125321

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables MHC class Ib protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular defense response TAS
Traceable Author Statement
more info
 PubMed 
involved_in immune response-regulating signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
killer cell immunoglobulin-like receptor 3DL2
Names
CD158 antigen-like family member K
KIR antigen 3DL2
MHC class I NK cell receptor
killer Ig receptor
killer cell immunoglobulin-like receptor 2DL2
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
killer-cell immunoglobulin-like receptor
natural killer-associated transcript 4
p70 NK receptor CL-5
p70 killer cell inhibitory receptor
p70 natural killer cell receptor clone CL-5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012802.2 RefSeqGene

    Range
    5124..21888
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001242867.2 → NP_001229796.1  killer cell immunoglobulin-like receptor 3DL2 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001229796.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AF262967, AY059418, BP384308, X93596
    Consensus CDS
    CCDS58677.1
    UniProtKB/TrEMBL
    A0A0G2JLM7, A0A0G2JLX7, A0A0G2JM59, A0A0G2JMS0, A0A0G2JN45, A0A0G2JP67, A0A1W2PPV3
    Related
    ENSP00000270442.5, ENST00000270442.6
    Conserved Domains (3) summary
    cd05711
    Location:28 → 117
    Ig_FcalphaRI; Immunoglobulin (IG)-like domain of of FcalphaRI
    smart00410
    Location:35 → 98
    IG_like; Immunoglobulin like
    cl11960
    Location:223 → 311
    Ig; Immunoglobulin domain

  2. NM_006737.4 → NP_006728.2  killer cell immunoglobulin-like receptor 3DL2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_006728.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AF263617, L41270
    Consensus CDS
    CCDS12906.1
    UniProtKB/Swiss-Prot
    P43630, Q13238, Q14947, Q14948, Q92684, Q95366, Q95367, Q95368
    UniProtKB/TrEMBL
    A0A0C4ZLV9, A0A0C4ZNW6, A0A0G2JLU7, A0A0G2JLZ4, A0A0G2JPQ5, A0A0U1V1E6, A0A0U1WN45, A0A0U1WN54, A0A0U1WNF3, A0A0U1WNF5, A0A0U4YTC8, A0A0U5FNF5, A0A0U5GHD6, A0A110BGM1, A0A110BGU4, A0A110BIQ9, A0A120N617, Q6H2F6, Q8NHK6
    Related
    ENSP00000325525.3, ENST00000326321.7
    Conserved Domains (3) summary
    cd00096
    Location:224 → 228
    Ig; Ig strand A [structural motif]
    cd05711
    Location:28 → 117
    IgC2_D2_LILR_KIR_like; Second immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors, Natural killer inhibitory receptors (KIRs) and similar domains; member of Immunoglobulin Constant-2 set of IgSF domains
    cl11960
    Location:223 → 311
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    54850443..54867207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047438795.1 → XP_047294751.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107300.1 Reference GRCh38.p14 PATCHES

    Range
    151886..160579
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107301.1 Reference GRCh38.p14 PATCHES

    Range
    152086..168847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332031.1 → XP_054188006.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107302.1 Reference GRCh38.p14 PATCHES

    Range
    152076..168078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107303.1 Reference GRCh38.p14 PATCHES

    Range
    284847..290344
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    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107304.1 Reference GRCh38.p14 PATCHES

    Range
    179497..196283
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332042.1 → XP_054188017.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107305.1 Reference GRCh38.p14 PATCHES

    Range
    152093..157552
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107306.1 Reference GRCh38.p14 PATCHES

    Range
    151039..167809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332047.1 → XP_054188022.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107307.1 Reference GRCh38.p14 PATCHES

    Range
    152038..160747
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107308.1 Reference GRCh38.p14 PATCHES

    Range
    87763..89622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107309.1 Reference GRCh38.p14 PATCHES

    Range
    152076..160788
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107310.1 Reference GRCh38.p14 PATCHES

    Range
    209643..218355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107312.1 Reference GRCh38.p14 PATCHES

    Range
    44779..61569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332053.1 → XP_054188028.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107313.1 Reference GRCh38.p14 PATCHES

    Range
    152069..168819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332055.1 → XP_054188030.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_016107314.1 Reference GRCh38.p14 PATCHES

    Range
    138433..143904
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NW_003571055.2 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    495695..512481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330169.1 → XP_054186144.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_3

Genomic

  1. NW_003571056.2 Reference GRCh38.p14 ALT_REF_LOCI_3

    Range
    830321..839009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_4

Genomic

  1. NW_003571057.2 Reference GRCh38.p14 ALT_REF_LOCI_4

    Range
    858288..860147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_5

Genomic

  1. NW_003571058.2 Reference GRCh38.p14 ALT_REF_LOCI_5

    Range
    832361..849147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054330956.1 → XP_054186931.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_6

Genomic

  1. NW_003571059.2 Reference GRCh38.p14 ALT_REF_LOCI_6

    Range
    769011..785797
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331237.1 → XP_054187212.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

  1. NW_003571060.1 Reference GRCh38.p14 ALT_REF_LOCI_7

    Range
    754833..771582
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054331511.1 → XP_054187486.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_9

Genomic

  1. NT_187693.1 Reference GRCh38.p14 ALT_REF_LOCI_9

    Range
    833012..849776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333647.1 → XP_054189622.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_10

Genomic

  1. NT_187636.1 Reference GRCh38.p14 ALT_REF_LOCI_10

    Range
    8305..25091 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333426.1 → XP_054189401.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_11

Genomic

  1. NT_187637.1 Reference GRCh38.p14 ALT_REF_LOCI_11

    Range
    1584..18370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333430.1 → XP_054189405.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_12

Genomic

  1. NT_187638.1 Reference GRCh38.p14 ALT_REF_LOCI_12

    Range
    2033..18765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333431.1 → XP_054189406.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

    UniProtKB/TrEMBL
    A0A376A965

Reference GRCh38.p14 ALT_REF_LOCI_13

Genomic

  1. NT_187639.1 Reference GRCh38.p14 ALT_REF_LOCI_13

    Range
    2159..18909 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333433.1 → XP_054189408.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_14

Genomic

  1. NT_187640.1 Reference GRCh38.p14 ALT_REF_LOCI_14

    Range
    2957..8392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_15

Genomic

  1. NT_187641.1 Reference GRCh38.p14 ALT_REF_LOCI_15

    Range
    13980..30766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333437.1 → XP_054189412.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_16

Genomic

  1. NT_187642.1 Reference GRCh38.p14 ALT_REF_LOCI_16

    Range
    1723..18474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333440.1 → XP_054189415.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_17

Genomic

  1. NT_187643.1 Reference GRCh38.p14 ALT_REF_LOCI_17

    Range
    1850..18600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333442.1 → XP_054189417.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_18

Genomic

  1. NT_187644.1 Reference GRCh38.p14 ALT_REF_LOCI_18

    Range
    1839..18625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_19

Genomic

  1. NT_187645.1 Reference GRCh38.p14 ALT_REF_LOCI_19

    Range
    1850..18614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333449.1 → XP_054189424.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_20

Genomic

  1. NT_187668.1 Reference GRCh38.p14 ALT_REF_LOCI_20

    Range
    3035..8532 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_21

Genomic

  1. NT_187669.1 Reference GRCh38.p14 ALT_REF_LOCI_21

    Range
    1850..18600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333452.1 → XP_054189427.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_22

Genomic

  1. NT_187670.1 Reference GRCh38.p14 ALT_REF_LOCI_22

    Range
    2092..18878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333454.1 → XP_054189429.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_23

Genomic

  1. NT_187671.1 Reference GRCh38.p14 ALT_REF_LOCI_23

    Range
    129409..146154
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333462.1 → XP_054189437.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_25

Genomic

  1. NT_187673.1 Reference GRCh38.p14 ALT_REF_LOCI_25

    Range
    1851..18639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333463.1 → XP_054189438.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_26

Genomic

  1. NT_187674.1 Reference GRCh38.p14 ALT_REF_LOCI_26

    Range
    136461..153231
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333468.1 → XP_054189443.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_27

Genomic

  1. NT_187675.1 Reference GRCh38.p14 ALT_REF_LOCI_27

    Range
    220660..237446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333474.1 → XP_054189449.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_28

Genomic

  1. NT_187676.1 Reference GRCh38.p14 ALT_REF_LOCI_28

    Range
    126387..143157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333482.1 → XP_054189457.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_29

Genomic

  1. NT_187677.1 Reference GRCh38.p14 ALT_REF_LOCI_29

    Range
    127809..144573
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333488.1 → XP_054189463.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_30

Genomic

  1. NT_187683.1 Reference GRCh38.p14 ALT_REF_LOCI_30

    Range
    124676..141426
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333494.1 → XP_054189469.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_31

Genomic

  1. NT_187684.1 Reference GRCh38.p14 ALT_REF_LOCI_31

    Range
    1850..18618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333497.1 → XP_054189472.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_32

Genomic

  1. NT_187685.1 Reference GRCh38.p14 ALT_REF_LOCI_32

    Range
    2207..18974 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_33

Genomic

  1. NT_187686.1 Reference GRCh38.p14 ALT_REF_LOCI_33

    Range
    2185..18971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333500.1 → XP_054189475.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_34

Genomic

  1. NT_187687.1 Reference GRCh38.p14 ALT_REF_LOCI_34

    Range
    1850..18614 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333503.1 → XP_054189478.1  killer cell immunoglobulin-like receptor 3DL2 isoform X1

Reference GRCh38.p14 ALT_REF_LOCI_35

Genomic

  1. NT_113949.2 Reference GRCh38.p14 ALT_REF_LOCI_35

    Range
    2842..11554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    57944772..57961522
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43630.1 GenPept UniProtKB/Swiss-Prot:P43630

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