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Slc28a2b solute carrier family 28 member 2b [ Mus musculus (house mouse) ]

Gene ID: 381417, updated on 2-Nov-2024

Summary

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Official Symbol
Slc28a2bprovided by MGI
Official Full Name
solute carrier family 28 member 2bprovided by MGI
Primary source
MGI:MGI:3702173
See related
Ensembl:ENSMUSG00000079071 AllianceGenome:MGI:3702173
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm14085
Summary
Predicted to enable neurotransmitter transmembrane transporter activity and nucleoside transmembrane transporter activity. Predicted to be involved in several processes, including nucleoside transport; protein localization to cell surface; and purine nucleobase transmembrane transport. Predicted to be located in apicolateral plasma membrane; coated vesicle; and vesicle membrane. Predicted to be active in plasma membrane. Orthologous to human SLC28A2 (solute carrier family 28 member 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in small intestine adult (RPKM 11.0), large intestine adult (RPKM 7.3) and 7 other tissues See more
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Genomic context

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See Slc28a2b in Genome Data Viewer
Location:
2 E5; 2 60.63 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (122315422..122358521)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (122484941..122528040)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 Neighboring gene STARR-positive B cell enhancer ABC_E7855 Neighboring gene BMP and activin membrane-bound inhibitor, pseudogene (Xenopus laevis) Neighboring gene STARR-positive B cell enhancer ABC_E11154 Neighboring gene predicted gene, 34325 Neighboring gene predicted gene, 17958 Neighboring gene glycine amidinotransferase (L-arginine:glycine amidinotransferase)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  2. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  3. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  4. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article
  5. Functional annotation of a full-length mouse cDNA collection. Kawai J, et al. Nature, 2001 Feb 8. PMID 11217851

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables neurotransmitter transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables nucleoside transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables nucleoside:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleoside:sodium symporter activity ISO
Inferred from Sequence Orthology
more info
  
enables purine nucleobase transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables purine nucleoside transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables purine nucleoside transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
enables pyrimidine- and adenosine-specific:sodium symporter activity ISO
Inferred from Sequence Orthology
more info
  
enables uridine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in adenosine transport ISO
Inferred from Sequence Orthology
more info
  
involved_in inosine transport ISO
Inferred from Sequence Orthology
more info
  
involved_in neurotransmitter transport ISO
Inferred from Sequence Orthology
more info
  
involved_in nucleoside transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nucleoside transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to cell surface ISO
Inferred from Sequence Orthology
more info
  
involved_in purine nucleobase transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in purine nucleoside transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in pyrimidine-containing compound transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
involved_in retina homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retina homeostasis ISO
Inferred from Sequence Orthology
more info
  
involved_in uridine transmembrane transport ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in apicolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in coated vesicle ISO
Inferred from Sequence Orthology
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in vesicle membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085518.1 → NP_001078987.1  solute carrier family 28 (sodium-coupled nucleoside transporter), member 2-like

    See identical proteins and their annotated locations for NP_001078987.1

    Status: VALIDATED

    Source sequence(s)
    AL954714
    Consensus CDS
    CCDS38223.1
    UniProtKB/TrEMBL
    A2AWR5, Q7TMQ0
    Related
    ENSMUSP00000106150.3, ENSMUST00000110521.3
    Conserved Domains (4) summary
    TIGR00804
    Location:176 → 587
    nupC; nucleoside transporter
    pfam01773
    Location:181 → 250
    Nucleos_tra2_N; Na+ dependent nucleoside transporter N-terminus
    pfam07662
    Location:364 → 587
    Nucleos_tra2_C; Na+ dependent nucleoside transporter C-terminus
    pfam07670
    Location:264 → 358
    Gate; Nucleoside recognition

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    122315422..122358521
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017319077.2 → XP_017174566.1  solute carrier family 28 (sodium-coupled nucleoside transporter), member 2-like isoform X1

    Conserved Domains (1) summary
    TIGR00804
    Location:176 → 564
    nupC; nucleoside transporter
Nucleotide Protein Strain
Heading Accession and Version

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