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Ccdc180 coiled-coil domain containing 180 [ Mus musculus (house mouse) ]

Gene ID: 381522, updated on 2-Nov-2024

Summary

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Official Symbol
Ccdc180provided by MGI
Official Full Name
coiled-coil domain containing 180provided by MGI
Primary source
MGI:MGI:2685871
See related
Ensembl:ENSMUSG00000035539 AllianceGenome:MGI:2685871
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1025; E230008N13Rik
Summary
Is expressed in brain and reproductive system. Orthologous to human CCDC180 (coiled-coil domain containing 180). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in testis adult (RPKM 7.2), lung adult (RPKM 0.8) and 1 other tissue See more
Orthologs
human all
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Genomic context

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See Ccdc180 in Genome Data Viewer
Location:
4 B1; 4 24.42 cM
Exon count:
39
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (45890303..45950774)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (45890303..45950774)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 1 family, member B1 Neighboring gene insulin-like growth factor binding protein-like 1 Neighboring gene STARR-seq mESC enhancer starr_10113 Neighboring gene STARR-seq mESC enhancer starr_10114 Neighboring gene STRA6-like Neighboring gene tudor domain containing 7 Neighboring gene tropomodulin 1 Neighboring gene predicted gene, 52729

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  2. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
coiled-coil domain-containing protein 180

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198660.2 → NP_941062.2  coiled-coil domain-containing protein 180

    Status: PROVISIONAL

    Source sequence(s)
    AL772381
    Consensus CDS
    CCDS57275.1
    UniProtKB/TrEMBL
    F6QNN0, J3QNE4
    Related
    ENSMUSP00000136714.2, ENSMUST00000178561.8
    Conserved Domains (3) summary
    pfam04497
    Location:1009 → 1101
    Pox_E2-like; Poxviridae protein
    pfam14643
    Location:148 → 616
    DUF4455; Domain of unknown function (DUF4455)
    pfam14644
    Location:1346 → 1543
    DUF4456; Domain of unknown function (DUF4456)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    45890303..45950774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017320287.2 → XP_017175776.1  coiled-coil domain-containing protein 180 isoform X1

    UniProtKB/TrEMBL
    F6QNN0
    Conserved Domains (2) summary
    pfam14643
    Location:148 → 616
    DUF4455; Domain of unknown function (DUF4455)
    pfam14644
    Location:1317 → 1521
    DUF4456; Domain of unknown function (DUF4456)

  2. XM_017320289.1 → XP_017175778.1  coiled-coil domain-containing protein 180 isoform X2

    Conserved Domains (1) summary
    pfam14643
    Location:148 → 616
    DUF4455; Domain of unknown function (DUF4455)

  3. XM_017320290.1 → XP_017175779.1  coiled-coil domain-containing protein 180 isoform X3

    Conserved Domains (1) summary
    pfam14643
    Location:148 → 616
    DUF4455; Domain of unknown function (DUF4455)

  4. XM_017320291.2 → XP_017175780.1  coiled-coil domain-containing protein 180 isoform X4

    Conserved Domains (1) summary
    pfam14643
    Location:148 → 616
    DUF4455; Domain of unknown function (DUF4455)

RNA

  1. XR_004941930.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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