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nAChRbeta1 - nicotinic Acetylcholine Receptor beta1

Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Involved in cholinergic synaptic transmission. Located in postsynaptic membrane. Is expressed in several structures, including adult head; cell body rind region; ganglia; optic lobe narrow field columnar neurons; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; cocaine abuse; congenital myasthenic syndrome (multiple); and respiratory system cancer (multiple). Orthologous to several human genes including CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to nAChRbeta1

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Species Gene Architecture aa